Background and aims Although oral berberine, a natural compound extracted from the
Chinese herbal medicine curcumin, has low bioavailability, it is still effective in suppressing …

Overnutrition and modern diets containing high proportions of saturated fat are among the
major factors contributing to a low-grade state of inflammation, hyperglycemia and …

Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …

Atherosclerosis is a chronic inflammatory disease of the vascular system that is
characterized by the deposition of modified lipoproteins, accumulation of immune cells, and …

Since adipose tissue (AT) can upregulate pro-inflammatory interleukins (ILs) via storing
extra lipids in obesity, obesity is considered the leading cause of chronic low-grade …

Abstract Background Radix Ginseng, one of the well-known medicinal herbs, has been used
in the management of diabetes and its complications for more than 1000 years. Purpose The …

T2DM, as a typical metabolic inflammatory disease, is under the joint regulation of
environmental factors and genetics, combining with a variety of epigenetic changes. Apart …

Preventing islet β‐cells death is crucial for treating type 2 diabetes mellitus (T2DM).
Currently, clinical drugs are being developed to improve the quality of T2DM care and self …

Overweight, obesity, and type 2 diabetes mellitus pose global health problems that are ever-
increasing. A chronic low-grade inflammatory status and the presence of various pro …

CD36 is a multiligand receptor contributing to glucose and lipid metabolism, immune
response, inflammation, thrombosis, and fibrosis. A wide range of tissue expression includes …