[HTML][HTML] Cannabidiol (CBD) as a promising anti-cancer drug

ES Seltzer, AK Watters, D MacKenzie, LM Granat… - Cancers, 2020 - mdpi.com
Recently, cannabinoids, such as cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC),
have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a …

Cannabinoids as anticancer drugs: current status of preclinical research

B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …

[HTML][HTML] The molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NF-κB pathway under oxidative stress

SA Ekiner, A Gęgotek, E Skrzydlewska - Redox Biology, 2022 - Elsevier
Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …

Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

The endocannabinoid system: A target for cancer treatment

C Laezza, C Pagano, G Navarra, O Pastorino… - International journal of …, 2020 - mdpi.com
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

[HTML][HTML] Extracellular vesicles of cannabis with high CBD content induce anticancer signaling in human hepatocellular carcinoma

T Tajik, K Baghaei, VE Moghadam, N Farrokhi… - Biomedicine & …, 2022 - Elsevier
Plant-derived extracellular vesicles (EVs) have been the topic of interest in recent years due
to their proven therapeutic properties. Intact or manipulated plant EVs have shown …

Inclusion complexes of cannabidiol with β-cyclodextrin and its derivative: Physicochemical properties, water solubility, and antioxidant activity

H Li, SL Chang, TR Chang, Y You, XD Wang… - Journal of Molecular …, 2021 - Elsevier
Cannabidiol (CBD), which has a wide variety of biological activities, is one of the
phytocannabinoids from Cannabis sativa L. However, due to the poor aqueous solubility, its …

Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities

S Lal, A Shekher, AS Narula, H Abrahamse… - Pharmacological …, 2021 - Elsevier
Cannabis has long been used for healing and recreation in several regions of the world.
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been …

Molecular mechanism of cannabinoids in cancer progression

C Pagano, G Navarra, L Coppola, M Bifulco… - International Journal of …, 2021 - mdpi.com
Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors
eliciting several physiological effects both in the central and peripheral nervous systems and …