Nerve density and neuronal biomarkers in cancer
SR Ali, M Jordan, P Nagarajan, M Amit - Cancers, 2022 - mdpi.com
Simple Summary Researchers have shown that tumor biomarkers and increased nerve
density are important clinical tools for determining cancer prognosis and developing …
density are important clinical tools for determining cancer prognosis and developing …
[HTML][HTML] Overexpression of stathmin promotes metastasis and growth of malignant solid tumors: a systemic review and meta-analysis
R Biaoxue, L Hua, G Wenlong, Y Shuanying - Oncotarget, 2016 - ncbi.nlm.nih.gov
Stathmin has been investigated to be involved in development and progress of malignant
tumors. This study was to clarify the relationship between expression of stathmin and tumors …
tumors. This study was to clarify the relationship between expression of stathmin and tumors …
Merkel cell polyomavirus small T antigen mediates microtubule destabilization to promote cell motility and migration
LM Knight, G Stakaityte, JJ Wood… - Journal of …, 2015 - Am Soc Microbiol
Merkel cell carcinoma (MCC) is an aggressive skin cancer of neuroendocrine origin with a
high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes …
high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes …
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway
L Zhao, D Zhang, Q Shen, M Jin, Z Lin, H Ma, S Huang… - Oncogene, 2019 - nature.com
Tumor metastasis is the main cause of death in advanced colorectal cancer. Our previous
research showed that upregulation of KIAA1199 predicted poorer outcomes, and promoted …
research showed that upregulation of KIAA1199 predicted poorer outcomes, and promoted …
Repositioning VU‐0365114 as a novel microtubule‐destabilizing agent for treating cancer and overcoming drug resistance
YY Hsieh, JL Du, PM Yang - Molecular Oncology, 2024 - Wiley Online Library
Microtubule‐targeting agents represent one of the most successful classes of anticancer
agents. However, the development of drug resistance and the appearance of adverse effects …
agents. However, the development of drug resistance and the appearance of adverse effects …
Sulforaphane metabolites cause apoptosis via microtubule disruption in cancer
Y Zhou, G Yang, H Tian, Y Hu, S Wu… - Endocrine-Related …, 2018 - erc.bioscientifica.com
Sulforaphane (SFN) inhibited growth in many cancers, but its half-life is 2 h in circulation.
However, its metabolites, sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl …
However, its metabolites, sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl …
Formulation of polymeric nanoparticles loaded sorafenib; evaluation of cytotoxicity, molecular evaluation, and gene expression studies in lung and breast cancer cell …
AAH Abdellatif, AT Ali, A Bouazzaoui… - Nanotechnology …, 2022 - degruyter.com
Sorafenib (SFB) is an anticancer drug with sparingly water solubility and reduced
bioavailability. Nanoformulation of SFB can increase its dissolution rate and solubility. The …
bioavailability. Nanoformulation of SFB can increase its dissolution rate and solubility. The …
Zyxin (ZYX) promotes invasion and acts as a biomarker for aggressive phenotypes of human glioblastoma multiforme
XM Wen, T Luo, Y Jiang, LH Wang, Y Luo… - Laboratory …, 2020 - nature.com
Glioblastoma multiforme (GBM) is characterized by highly invasive growth, which leads to
extensive infiltration and makes complete tumor excision difficult. Since cytoskeleton …
extensive infiltration and makes complete tumor excision difficult. Since cytoskeleton …
In vitro neutralization of autocrine IL‑10 affects Op18/stathmin signaling in non‑small cell lung cancer cells
Y Zhao, S Chen, F Shen, D Long, T Yu… - Oncology …, 2019 - spandidos-publications.com
Our previous studies have identified that silencing oncoprotein 18 (Op18)/stathmin via RNA
interference (RNAi) inhibited autocrine interleukin‑10 (IL‑10) and enhanced the sensitivity to …
interference (RNAi) inhibited autocrine interleukin‑10 (IL‑10) and enhanced the sensitivity to …
Stathmin destabilizing microtubule dynamics promotes malignant potential in cancer cells by epithelial-mesenchymal transition
Y Lu, C Liu, YF Xu, H Cheng, S Shi, CT Wu… - Hepatobiliary & Pancreatic …, 2014 - Elsevier
Background Stathmin is a ubiquitous cytosolic regulatory phosphoprotein and is
overexpressed in different human malignancies. The main physiological function of stathmin …
overexpressed in different human malignancies. The main physiological function of stathmin …