OnabotulinumtoxinA alters inflammatory gene expression and immune cells in chronic headache patients

L Gfrerer, W Xu, W Austen Jr, S Ashina, A Melo-Carrillo… - Brain, 2022 - academic.oup.com
Occipital headache, the perception of pain in the back of the head, is commonly described
by patients diagnosed with migraine, tension-type headache, and occipital neuralgia. The …

Surgical Management of Headache Disorders-A Systematic Review of the Literature

MHJ Hazewinkel, L Knoedler, PG Mathew… - Current Neurology and …, 2024 - Springer
Despite these developments, challenges persist, particularly related to appropriate patient
selection, insurance coverage, delays in diagnosis and surgical treatment, and the absence …

Relative pain reduction and duration of nerve block response predict outcomes in headache surgery: A prospective cohort study

L Knoedler, C Chartier, ME Casari… - Plastic and …, 2023 - journals.lww.com
Background: Experts agree that nerve block (NB) response is an important tool in headache
surgery screening. However, the predictive value of NBs remains to be proven in a …

[HTML][HTML] RPNI, TMR, and reset neurectomy/relocation nerve grafting after nerve transection in headache surgery

L Gfrerer, FK Wong, K Hickle, KR Eberlin… - … Surgery–Global Open, 2022 - journals.lww.com
Background: In the context of headache surgery, greater occipital nerve (GON) transection is
performed when the nerve appears severely damaged, if symptoms are recurrent or …

Treatment delay from onset of occipital neuralgia symptoms to treatment with nerve decompression surgery: a prospective cohort study

MHJ Hazewinkel, K Remy, G Black, S Tseng… - Pain …, 2024 - academic.oup.com
Background The aims of this study were to (1) evaluate the time between onset of occipital
neuralgia symptoms and nerve decompression surgery,(2) perform a cost comparison …

[HTML][HTML] Frontal site surgery for chronic migraine therapy

G Raposio, A Antonini, A Gualdi… - Acta Bio Medica: Atenei …, 2023 - ncbi.nlm.nih.gov
Methods: In this work, we describe our experience with this type of surgery. From 2011 to
2022, we treated 98 cases suffering from chronic migraine not responsive to drugs with …

Revisiting the role of occipital artery resection in greater occipital nerve decompression

JE Janis, H ElHawary, A Schoenbrunner… - Plastic and …, 2022 - journals.lww.com
Background: Greater occipital nerve surgery has been shown to improve headaches caused
by nerve compression. There is a paucity of data, however, specifically regarding the …

[HTML][HTML] Nonsurgical treatment of neuralgia and cervicogenic headache: a systematic review and meta-analysis

MHJ Hazewinkel, T Bink, CA Hundepool… - … Surgery–Global Open, 2022 - journals.lww.com
Background: Extracranial compression of peripheral sensory nerves is one of many origins
of chronic headaches. Identifying these patients can be difficult, and they are often …

[HTML][HTML] The peripheral nerve surgeon's role in the management of neuropathic pain

SP Caragher, KS Khouri, FV Raasveld… - … Surgery–Global Open, 2023 - journals.lww.com
Neuropathic pain (NP) underlies significant morbidity and disability worldwide. Although
pharmacologic and functional therapies attempt to address this issue, they remain …

[HTML][HTML] Refractory occipital neuralgia treatment with nerve decompression surgery: a case series

WG Austen Jr, K Remy, K Packowski… - Frontiers in …, 2023 - frontiersin.org
Background The management of refractory occipital neuralgia (ON) can be challenging.
Selection criteria for occipital nerve decompression surgery are not well defined in terms of …