Human papilloma virus-associated cervical cancer and health disparities

P Olusola, HN Banerjee, JV Philley, S Dasgupta - Cells, 2019 - mdpi.com
Cervical cancer develops through persistent infection with high-risk human papilloma virus
(hrHPV) and is a leading cause of death among women worldwide and in the United States …

Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis

H Kelly, Y Benavente, MA Pavon, S De Sanjose… - British journal of …, 2019 - nature.com
Background To conduct a meta-analysis of performance of DNA methylation in women with
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …

The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review

WW Kremer, RDM Steenbergen… - … Journal of Obstetrics …, 2021 - Wiley Online Library
This paper briefly reviews the role of hypermethylation of host cell genes in cervical
carcinogenesis and discusses potential clinical applications of methylation analysis in the …

[HTML][HTML] Virtues and weaknesses of DNA methylation as a test for cervical cancer prevention

AT Lorincz - Acta cytologica, 2016 - karger.com
Epigenetics is the study of heritable and non-heritable genetic coding that is additive to
information contained within classical DNA base pair sequences. Differential methylation …

[HTML][HTML] HPV-based cervical screening: Rationale, expectations and future perspectives of the new Dutch screening programme

NJ Polman, PJF Snijders, GG Kenter, J Berkhof… - Preventive …, 2019 - Elsevier
Based on scientific data showing that HPV testing provides better protection against cervical
precancer and cancer than cytology, in 2011 the Dutch Health Council advised the Minister …

Methylation Analysis of the FAM19A4 Gene in Cervical Scrapes Is Highly Efficient in Detecting Cervical Carcinomas and Advanced CIN2/3 Lesions

LMA De Strooper, CJLM Meijer, J Berkhof… - Cancer Prevention …, 2014 - AACR
Primary testing for human papillomavirus (HPV) in cervical screening requires triage to
differentiate women with transient infection from those with persistent infection who require …

Cervical cancer risk in HPV‐positive women after a negative FAM19A4/mir124‐2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow‐up

LMA De Strooper, J Berkhof… - … journal of cancer, 2018 - Wiley Online Library
DNA methylation analysis of cervical scrapes using FAM19A4 and mir124‐2 genes has
shown a good clinical performance in detecting cervical cancer and advanced CIN lesions …

Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer

MA Clarke, P Luhn, JC Gage, C Bodelon… - … journal of cancer, 2017 - Wiley Online Library
Human papillomavirus (HPV) testing has been recently introduced as an alternative to
cytology for cervical cancer screening. However, since most HPV infections clear without …

Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high‐risk HPV‐positive …

R Luttmer, LMA De Strooper, J Berkhof… - … journal of cancer, 2016 - Wiley Online Library
Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to
adequately detect high‐grade cervical intraepithelial neoplasia and cervical cancer (≥ …

The early detection of cervical cancer. The current and changing landscape of cervical disease detection

A Shiraz, R Crawford, N Egawa, H Griffin… - …, 2020 - Wiley Online Library
Cervical cancer prevention has undergone dramatic changes over the past decade. With the
introduction of human papillomavirus (HPV) vaccination, some countries have seen a …