A randomized phase 2 study of PBPC mobilization by stem cell factor and filgrastim in heavily pretreated patients with Hodgkin's disease or non-Hodgkin's lymphoma

P Stiff, R Gingrich, S Luger, MR Wyres… - Bone marrow …, 2000 - nature.com
This randomized, controlled study compared the ability to mobilize and collect an optimal
target yield of 5× 10 6 CD34+ cells/kg using stem cell factor (SCF; 20 μg/kg/day) plus …

Clinical significance of CD34+ cell dose in long-term engraftment following autologous peripheral blood stem cell transplantation

JA Perez-Simon, A Martin, D Caballero… - Bone marrow …, 1999 - nature.com
The number of CD34+ cells has been described as the best parameter for predicting the
quality of engraftment in peripheral blood progenitor cell (PBPC) transplantation in the early …

Predictive factors for a successful mobilization of peripheral blood CD34+ cells in multiple myeloma

G Perea, A Sureda, R Martino, A Altés, C Martinez… - Annals of …, 2001 - Springer
We analyzed the prognostic factors for a successful mobilization and peripheral blood stem
cell collection in a series of 57 consecutive patients with multiple myeloma (MM); a new …

Poor peripheral blood stem cell mobilization affects long‐term outcomes in multiple myeloma patients undergoing autologous stem cell transplantation

JS Moreb, M Byrne, I Shugarman, F Zou… - Journal of clinical …, 2018 - Wiley Online Library
Background Peripheral blood stem cell (PBSC) mobilization is routinely undertaken prior to
autologous stem cell transplantation (ASCT) in patients with multiple myeloma (MM). A …

Association of post-thaw viable CD34+ cells and CFU-GM with time to hematopoietic engraftment

H Yang, JP Acker, M Cabuhat, B Letcher… - Bone marrow …, 2005 - nature.com
In all, 78 peripheral hematopoietic progenitor cell collections from 52 patients were
evaluated using our previously published validated post-thaw assays at the time of …

Effect of CD34+ cell dose on hematopoietic reconstitution and outcome in 508 patients with multiple myeloma undergoing autologous peripheral blood stem cell …

J Klaus, D Herrmann, I Breitkreutz… - European journal of …, 2007 - Wiley Online Library
Background: We analyzed the hematopoietic reconstitution and outcome of 508 patients
with multiple myeloma (MM) with respect to the number of CD34+ cells reinfused at our …

Role of nonmyeloablative allogeneic stem-cell transplantation after failure of autologous transplantation in patients with lymphoproliferative malignancies

K Branson, R Chopra, PD Kottaridis… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: Conventional allogeneic stem-cell transplantation (SCT) after a prior failed
autograft is associated with a transplant-related mortality rate of 50% to 80%. The aim of the …

Regulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing

P Alvarez, E Carrillo, C Vélez… - BioMed research …, 2013 - Wiley Online Library
Regulation of hematopoietic stem cell release, migration, and homing from the bone marrow
(BM) and of the mobilization pathway involves a complex interaction among adhesion …

[HTML][HTML] In and out of the niche: perspectives in mobilization of hematopoietic stem cells

M Mohty, AD Ho - Experimental hematology, 2011 - Elsevier
Several stem cell mobilization strategies have been employed in the past 2 decades,
including chemotherapy, hematopoietic growth factors, and chemotherapy plus growth …

Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors

PH Miller, AMS Cheung, PA Beer… - Blood, The Journal …, 2013 - ashpublications.org
Better methods to characterize normal human hematopoietic cells with short-term
repopulating activity cells (STRCs) are needed to facilitate improving recovery rates in …