Growth hormone protects against ovarian granulosa cell apoptosis: Alleviation oxidative stress and enhancement mitochondrial function

J Wang, J Wu, Y Zhang, J Zhang, W Xu, C Wu… - Reproductive …, 2021 - Elsevier
Growth hormone (GH) is a polypeptide hormone that could reduce the mitochondria-
mediated oxidative stress and improve the mitochondrial function. However, the …

[HTML][HTML] Growth hormone (GH) improvement of ovarian responses and pregnancy outcome in poor ovarian responders: a randomized study

L Safdarian, M Aghahosseini, A Alyasin… - Asian Pacific Journal …, 2019 - ncbi.nlm.nih.gov
Recent evidence has emphasized growth hormone benefits in increasing the ovarian
response and improving the pregnancy rate in poor responders (POR), caused by aging …

British Fertility Society Policy and Practice Committee: adjuvants in IVF: evidence for good clinical practice

LG Nardo, T El-Toukhy, J Stewart, AH Balen… - Human …, 2015 - Taylor & Francis
Optimisation of the environment favourable for satisfactory ovarian response to stimulation
and successful embryo implantation remains at the core of assisted conception …

[HTML][HTML] The value of growth hormone supplements in ART for poor ovarian responders

D de Ziegler, I Streuli, DR Meldrum, C Chapron - Fertility and sterility, 2011 - Elsevier
Recently, three meta-analyses have concluded that cotreatment with GH improves assisted
reproduction outcome in poor controlled ovarian stimulation responders. Although generally …

Low-dose growth hormone supplementation increases clinical pregnancy rate in poor responders undergoing in vitro fertilisation

K Lattes, M Brassesco, M Gomez… - Gynecological …, 2015 - Taylor & Francis
Poor ovarian response (POR) often means low success rates after in vitro fertilisation (IVF).
We aim to study the impact of a low-dose growth hormone (GH) supplementation in …

Evidence‐based management of poor ovarian response

CA Venetis, EM Kolibianakis, TB Tarlatzi… - Annals of the New …, 2010 - Wiley Online Library
Poor ovarian response is not infrequent and represents one of the major therapeutic
challenges in in vitro fertilization. Although several tests have been proposed, which aim at …

[HTML][HTML] Efficacy of growth hormone supplementation with gonadotrophins in vitro fertilization for poor ovarian responders: an updated meta-analysis

X Yu, J Ruan, LP He, W Hu, Q Xu, J Tang… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Growth hormone (GH) is involved in the regulation of male and female infertility. Several
clinical studies reveal that adjuvant GH treatment has a possible role in vitro fertilization …

Insights from clinical experience in treating IVF poor responders

KJ Gonda, AD Domar, N Gleicher, RP Marrs - Reproductive biomedicine …, 2018 - Elsevier
Abstract 'Poor responders' is a term used to describe a subpopulation of IVF patients who do
not respond well to ovarian stimulation with gonadotrophins. While there is no standard …

[HTML][HTML] The clinical application of growth hormone and its biological and molecular mechanisms in assisted reproduction

P Pan, X Huang - International Journal of Molecular Sciences, 2022 - mdpi.com
Growth hormone (GH) has been used as a co-gonadotrophin in assisted reproduction,
particularly in poor ovarian responders. The application of GH has been alleged to activate …

[HTML][HTML] Growth hormone and reproduction: lessons learned from animal models and clinical trials

C Dosouto, J Calaf, A Polo, T Haahr… - Frontiers in …, 2019 - frontiersin.org
Growth Hormone (GH) has been considered as a therapeutic option to increase the number
of growing follicles during Assisted Reproductive Technology (ART) for more than 30 years …