This report summarizes current physiological and technical knowledge on esophageal
pressure (Pes) measurements in patients receiving mechanical ventilation. The respiratory …

The pathophysiological mechanisms by which mechanical ventilation can contribute to lung
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …

Purpose Severe ARDS is often associated with refractory hypoxemia, and early identification
and treatment of hypoxemia is mandatory. For the management of severe ARDS ventilator …

Positive end-expiratory pressure (PEEP) has been used during mechanical ventilation since
the first description of acute respiratory distress syndrome (ARDS). In the subsequent …

Respiratory mechanics refers to the expression of lung function through measures of
pressure and flow. From these measurements, a variety of derived indices can be …

The injurious effects of alveolar overdistention are well accepted, and there is little debate
regarding the importance of pressure and volume limitation during mechanical ventilation …

Identifying new effective treatments for the acute respiratory distress syndrome (ARDS),
including COVID-19 ARDS, remains a challenge. The field of ARDS investigation is moving …

It has been shown that mechanical ventilation in patients with, or at high-risk for, the
development of acute respiratory distress syndrome (ARDS) can be a double-edged sword …

It is well established that mechanical ventilation can injure the lung, producing an entity
known as ventilator-induced lung injury (VILI). There are various forms of VILI, including …

Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …