Tackling the emerging threat of antifungal resistance to human health
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …
Oral candidiasis: A disease of opportunity
T Vila, AS Sultan, D Montelongo-Jauregui… - Journal of fungi, 2020 - mdpi.com
Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …
Echinocandins–structure, mechanism of action and use in antifungal therapy
M Szymański, S Chmielewska… - Journal of enzyme …, 2022 - Taylor & Francis
With increasing number of immunocompromised patients as well as drug resistance in fungi,
the risk of fatal fungal infections in humans increases as well. The action of echinocandins is …
the risk of fatal fungal infections in humans increases as well. The action of echinocandins is …
Biodegradable hydrogel with thermo-response and hemostatic effect for photothermal enhanced anti-infective therapy
C Cao, N Yang, Y Zhao, D Yang, Y Hu, D Yang, X Song… - Nano Today, 2021 - Elsevier
Massive bleeding and infectious complication remain the leading cause of worldwide
trauma deaths. To tackle this issue, a platelet-inspired degradable antibacterial hydrogel …
trauma deaths. To tackle this issue, a platelet-inspired degradable antibacterial hydrogel …
Initial antimicrobial management of sepsis
Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …
Although community-acquired sepsis is more common, hospital-acquired infection is more …
[HTML][HTML] Phytochemical analysis and evaluation of antimicrobial, antioxidant, and antidiabetic activities of essential oils from Moroccan medicinal plants: Mentha …
N El Hachlafi, N Benkhaira, SH Al-Mijalli… - Biomedicine & …, 2023 - Elsevier
Mentha suaveolens, Lavandula stoechas, and Ammi visnaga are widely used in Moroccan
folk medicine against several pathological disorders, including diabetes and infectious …
folk medicine against several pathological disorders, including diabetes and infectious …
Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants
J Branco, IM Miranda, AG Rodrigues - Journal of Fungi, 2023 - mdpi.com
Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …
Southern Europe, and Latin America and is often involved in invasive infections that …
Emerging antifungal targets and strategies
M Ivanov, A Ćirić, D Stojković - International Journal of Molecular …, 2022 - mdpi.com
Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …
a significant healthcare burden. There is an emerging need for the development of novel …
Mechanistic Understanding of Candida albicans Biofilm Formation and Approaches for Its Inhibition
In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …
Fungicide effects on human fungal pathogens: cross-resistance to medical drugs and beyond
RW Bastos, L Rossato, GH Goldman… - PLoS Pathogens, 2021 - journals.plos.org
Fungal infections are underestimated threats that affect over 1 billion people, and Candida
spp., Cryptococcus spp., and Aspergillus spp. are the 3 most fatal fungi. The treatment of …
spp., Cryptococcus spp., and Aspergillus spp. are the 3 most fatal fungi. The treatment of …