Acute and chronic infectious prostatitis are the best understood of the prostate syndromes,
but they are the least frequent. In contrast, although chronic non-infectious prostatitis is the …

Plasmacytoid dendritic cells (PDCs), the main producers of type I IFN in response to viral
infection, are essential in antiviral immunity. In this study, we assessed the effect of human …

The concomitant use of diverse pattern recognition receptors (PRRs) by innate immune cells
can result in synergistic or inhibitory activities that profoundly influence anti-microbial …

Identifying β cell autoantigen-reactive T cells that are involved in the pathogenesis of type 1
diabetes has been troublesome for many laboratories. Disease-relevant autoreactive T cells …

It is widely accepted that Type 1 diabetes is a complex disease. Genetic predisposition and
environmental factors favour the triggering of autoimmune responses against pancreatic β …

Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells,
found within the islets of Langerhans in the pancreas, are destroyed by islet-infiltrating T …

Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)-presenting cells
is innovative and promising therapeutic approach to control undesired and harmful …

Background Chronic spontaneous urticaria (CSU) is the recurrence of urticaria without an
apparent trigger. Half of the patients with CSU have IgG autoantibodies to FcεRIα on dermal …

Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease. Short-term treatment with
agents targeting T cells, B cells and inflammatory cytokines to modify the disease course …

Objective: Antigen‐specific therapy targeting selective inhibition of autoreactive responses
holds promise for controlling multiple sclerosis (MS) without disturbing homeostasis of the …