The advent of major histocompatibility complex (MHC) tetramer technology has been a
major contribution to T cell immunology, because tetramer reagents permit detection of …

Quantitative assessment of immunogen‐specific T cell responses may provide a meaningful
surrogate marker of functional immunity in patients following haemopoietic stem cell …

Several lines of evidence suggest a definite and unique link between CNS demyelinating
diseases and autoimmune thyroid disease (AITD). The aim of the current study was to …

Abstract Objective Type 1 diabetes (T1D) is an autoimmune disorder in which autoreactive T
cells destroy insulin‐producing β‐cells. Interventions that preserve β‐cell function represent …

Context: Adiponectin is an adipocyte-derived cytokine with insulin-sensitizing and
antiinflammatory properties. These dual actions have not previously been examined in the …

Measurement of antigen-specific T cell responses is an adjunctive parameter to evaluate
protection induced by a previous Bordetella pertussis infection or vaccination. The …

Background Previously, we identified a major myeloid-derived proinflammatory
subpopulation of human blood dendritic cells which we termed slanDCs (eg Schäkel et …

Tumor cells may escape from the immune responses because of defective differentiation of
dendritic cells (DC). Recent studies have found an increased number of regulatory T cells …

Background Skin patch testing is still seen as the gold standard for the diagnosis of allergic
hypersensitivity. For several metals and for patients with a suspected adverse reaction to …

Background Chronic beryllium disease (CBD) is an occupational granulomatous disorder
characterized by hypersensitivity to beryllium, mediated by CD4+ T lymphocytes, and …