Epstein–Barr virus as a leading cause of multiple sclerosis: mechanisms and implications
Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …
[HTML][HTML] The CD8 T cell-Epstein-Barr virus-B cell trialogue: a central issue in multiple sclerosis pathogenesis
C Veroni, F Aloisi - Frontiers in immunology, 2021 - frontiersin.org
The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
Human herpesviruses 6a and 6b in brain diseases: Association versus causation
AL Komaroff, PE Pellett, S Jacobson - Clinical microbiology …, 2020 - Am Soc Microbiol
SUMMARY Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B),
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …
Role of environmental factors in multiple sclerosis
Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
Infections, vaccines and autoimmunity: a multiple sclerosis perspective
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative
disease that is associated with multiple environmental factors. Among suspected …
disease that is associated with multiple environmental factors. Among suspected …
Clinical onset and multiple sclerosis relapse after SARS-CoV-2 infection
A Pignolo, M Aprile, C Gagliardo, GM Giammanco… - Neurology …, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been
associated with several neurological disorders including headache, facial palsy …
associated with several neurological disorders including headache, facial palsy …
Identification of two highly antigenic epitope markers predicting multiple sclerosis in optic neuritis patients
H Sadam, A Pihlak, M Jaago, N Pupina, A Rähni… - …, 2021 - thelancet.com
Background Optic neuritis (ON) can occur as an isolated episode or will develop to multiple
sclerosis (MS) a chronic autoimmune disease. What predicts ON progression to MS remains …
sclerosis (MS) a chronic autoimmune disease. What predicts ON progression to MS remains …
[HTML][HTML] Illumination of molecular pathways in multiple sclerosis lesions and the immune mechanism of matrine treatment in EAE, a mouse model of MS
M Dou, X Zhou, L Li, M Zhang, W Wang… - Frontiers in …, 2021 - frontiersin.org
The etiology of multiple sclerosis (MS) is not clear, and the treatment of MS presents a great
challenge. This study aimed to investigate the pathogenesis and potential therapeutic …
challenge. This study aimed to investigate the pathogenesis and potential therapeutic …
[HTML][HTML] Analysis of herpesvirus infection and genome single nucleotide polymorphism risk factors in multiple sclerosis, Volga federal district, Russia
V Lezhnyova, Y Davidyuk, A Mullakhmetova… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a heterogeneous disease where herpesvirus infection and genetic
predisposition are identified as the most consistent risk factors. Serum and blood samples …
predisposition are identified as the most consistent risk factors. Serum and blood samples …
[HTML][HTML] The emerging roles of piezo1 channels in animal models of multiple sclerosis
K Yang, X He, Z Wu, Y Yin, H Pan, X Zhao… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative
disease in the central nervous system (CNS). Its pathogenesis is quite complex …
disease in the central nervous system (CNS). Its pathogenesis is quite complex …