From Monomers to Hexamers: A Theoretical Probability of the Neighbor Density Approach to Dissect Protein Oligomerization in Cells

H Chen, TY Chen - Analytical Chemistry, 2023 - ACS Publications
Deciphering the oligomeric state of proteins within cells is pivotal to understanding their role
in intricate cellular processes. With the recent advances in single-molecule localization …

Exploring Abeta42 Monomer Diffusive Dynamics on Fibril Surfaces through Molecular Simulations

YW Ma, GF Wang, MY Tsai - bioRxiv, 2024 - biorxiv.org
Alzheimer's disease is closely linked to the aggregation of Abeta42 peptides, which follow a
complex pathway involving primary nucleation and secondary processes. While previous …