Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …

The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

Alzheimer's disease (AD) is the most common chronic disease in the elderly, with a high
incidence rate. In recent years, deep learning has become popular in the field of medical …

Spurred by availability of automatic segmentation software, in vivo MRI investigations of
human hippocampal subfield volumes have proliferated in the recent years. However, a …

Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral
blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to …

Although the hippocampus is one of the most studied structures in the human brain, limited
quantitative data exist on its 3D organization, anatomical variability, and effects of disease …

There is growing evidence suggesting that vascular pathologies and dysfunction play a
critical role in cognitive impairment, clinical Alzheimer's disease, and dementia. Vascular …

Objective. Aging and AD are associated in some way, then it is reasonable to ask whether or
not it is possible to age without AD inexorably appearing at any moment, depending on the …