The role of copper homeostasis in brain disease
Y An, S Li, X Huang, X Chen, H Shan… - International journal of …, 2022 - mdpi.com
In the human body, copper is an important trace element and is a cofactor for several
important enzymes involved in energy production, iron metabolism, neuropeptide activation …
important enzymes involved in energy production, iron metabolism, neuropeptide activation …
The metal ion hypothesis of Alzheimer's disease and the anti-neuroinflammatory effect of metal chelators
LL Chen, YG Fan, LX Zhao, Q Zhang, ZY Wang - Bioorganic chemistry, 2023 - Elsevier
Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …
Recent advances in cancer therapeutic copper-based nanomaterials for antitumor therapy
R Aishajiang, Z Liu, T Wang, L Zhou, D Yu - Molecules, 2023 - mdpi.com
Copper serves as a vital microelement which is widely present in the biosystem, functioning
as multi-enzyme active site, including oxidative stress, lipid oxidation and energy …
as multi-enzyme active site, including oxidative stress, lipid oxidation and energy …
[HTML][HTML] Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists
P Ghosh, RA Fontanella, L Scisciola, A Pesapane… - Theranostics, 2023 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) have emerged as essential signaling molecules regulating
cell survival, death, inflammation, differentiation, growth, and immune response …
cell survival, death, inflammation, differentiation, growth, and immune response …
Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies
S Yang, Y Li, L Zhou, X Wang, L Liu, M Wu - Cell Death Discovery, 2024 - nature.com
Copper is an essential micronutrient that plays a pivotal role in numerous physiological
processes in virtually all cell types. Nevertheless, the dysregulation of copper homeostasis …
processes in virtually all cell types. Nevertheless, the dysregulation of copper homeostasis …
Structural characterization and anti-inflammatory effects of an arabinan isolated from Rehmannia glutinosa Libosch.
H Zhang, Y Yue, Q Zhang, L Liang, C Li, Y Chen… - Carbohydrate …, 2023 - Elsevier
Considering that natural polysaccharides are potential anti-inflammatory agents, in this
study, an arabinan (RGP70–2) was isolated and purified from Rehmannia glutinosa …
study, an arabinan (RGP70–2) was isolated and purified from Rehmannia glutinosa …
Heavy metal mediated progressive degeneration and its noxious effects on brain microenvironment
L Murumulla, LJM Bandaru, S Challa - Biological Trace Element Research, 2024 - Springer
Heavy metals, including lead (Pb), cadmium (Cd), arsenic (As), cobalt (Co), copper (Cu),
manganese (Mn), zinc (Zn), and others, have a significant impact on the development and …
manganese (Mn), zinc (Zn), and others, have a significant impact on the development and …
Association between serum copper, zinc, and selenium concentrations and depressive symptoms in the US adult population, NHANES (2011–2016)
D Huang, S Lai, S Zhong, Y Jia - BMC psychiatry, 2023 - Springer
Background Evidence suggests that alterations in serum trace element concentrations are
closely associated with mental illness. However, studies on the relationship between …
closely associated with mental illness. However, studies on the relationship between …
Mitochondrial DNA release mediated by TFAM deficiency promotes copper-induced mitochondrial innate immune response via cGAS-STING signalling in chicken …
Q Li, S Wang, P Guo, Y Feng, W Yu, H Zhang… - Science of The Total …, 2023 - Elsevier
Copper (Cu) is pollution metal that is a global concern due to its toxic effects. A recent study
found that the release of mitochondrial DNA (mtDNA) into the cytoplasm can activate the …
found that the release of mitochondrial DNA (mtDNA) into the cytoplasm can activate the …
Recent progress of copper-based nanomaterials in tumor-targeted photothermal therapy/photodynamic therapy
X Zhuo, Z Liu, R Aishajiang, T Wang, D Yu - Pharmaceutics, 2023 - mdpi.com
Nanotechnology, an emerging and promising therapeutic tool, may improve the
effectiveness of phototherapy (PT) in antitumor therapy because of the development of …
effectiveness of phototherapy (PT) in antitumor therapy because of the development of …