A common feature of pesticides: oxidative stress—the role of oxidative stress in pesticide‐induced toxicity

RO Sule, L Condon, AV Gomes - Oxidative medicine and …, 2022 - Wiley Online Library
Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …

Neurotoxicity of pesticides

JR Richardson, V Fitsanakis, RHS Westerink… - Acta …, 2019 - Springer
Pesticides are unique environmental contaminants that are specifically introduced into the
environment to control pests, often by killing them. Although pesticide application serves …

Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule

B Hébert, S Pietropaolo, S Même, B Laudier… - Orphanet journal of rare …, 2014 - Springer
Abstract Background Fragile X Syndrome (FXS) is the most common form of inherited
intellectual disability and is also associated with autism spectrum disorders. Previous …

Integration of toxicodynamic and toxicokinetic new approach methods into a weight-of-evidence analysis for pesticide developmental neurotoxicity assessment: A …

S Dobreniecki, E Mendez, A Lowit… - Regulatory Toxicology …, 2022 - Elsevier
Abstract DL-glufosinate ammonium (DL-GLF) is a registered herbicide for which a guideline
Developmental Neurotoxicity (DNT) study has been conducted. Offspring effects included …

Risk factors for brain health in agricultural work: a systematic review

ET Sturm, C Castro, A Mendez-Colmenares… - International journal of …, 2022 - mdpi.com
Certain exposures related to agricultural work have been associated with neurological
disorders. To date, few studies have included brain health measurements to link specific risk …

Food components and contaminants as (anti) androgenic molecules

D Marcoccia, M Pellegrini, M Fiocchetti, S Lorenzetti… - Genes & nutrition, 2017 - Springer
Androgens, the main male sex steroids, are the critical factors responsible for the
development of the male phenotype during embryogenesis and for the achievement of …

Pre-and postnatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice

A Laugeray, A Herzine, O Perche, B Hébert… - Frontiers in behavioral …, 2014 - frontiersin.org
Glufosinate ammonium (GLA) is one of the most widely used herbicides in agriculture. As is
the case for most pesticides, potential adverse effects of GLA have not been studied from the …

Glufosinate binds N-methyl-D-aspartate receptors and increases neuronal network activity in vitro

SR Lantz, CM Mack, K Wallace, EF Key, TJ Shafer… - Neurotoxicology, 2014 - Elsevier
Glufosinate (GLF) at high levels in mammals causes convulsions and amnesia through a
mechanism that is not completely understood. The structural similarity of GLF to glutamate …

Perinatal exposure to glufosinate ammonium herbicide impairs neurogenesis and neuroblast migration through cytoskeleton destabilization

A Herzine, A Laugeray, J Feat, A Menuet… - Frontiers in cellular …, 2016 - frontiersin.org
Neurogenesis, a process of generating functional neurons from neural precursors, occurs
throughout life in restricted brain regions such as the subventricular zone (SVZ). During this …

Mammalian toxicity of herbicides used in intensive GM crop farming

R Mesnage, M Antoniou - Herbicides, 2021 - Elsevier
The toxicity of major herbicides on mammalian physiology is reviewed, with a focus on
herbicides associated with agricultural systems employing genetically modified crops …