The aim of the review is to examine the role of growth factors and cytokines in the
management of Diabetic Foot Ulcers, such as platelet derived growth factor (PDGF) …

Abstract Insulin-Like Growth Factor 1 (IGF-1) is a phylogenetically ancient neurotrophic
hormone with crucial roles to play in CNS development and maturation. Recently, IGF-1 has …

Astrocytes negatively impact neuronal development in many models of neurodevelopmental
disorders (NDs); however, how they do this, and if mechanisms are shared across disorders …

Cell-free protein synthesis (CFPS) system is a simple, rapid, and sensitive tool that is devoid
of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and …

While the insulin receptor (IR) was found in the CNS decades ago, the brain was long
considered to be an insulin‐insensitive organ. This view is currently revisited, given …

It is generally assumed that human intelligence relies on efficient processing by neurons in
our brain. Although grey matter thickness and activity of temporal and frontal cortical areas …

Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …

What is the neurobiological basis of human intelligence? The brains of some people seem
to be more efficient than those of others. Understanding the biological foundations of these …

Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Much thought has been given to the impact of Amyloid Beta, Tau and Alpha-Synuclein in the
development of Alzheimer's disease (AD) and Parkinson's disease (PD), yet the clinical …