[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …
serious therapeutic consequences. The source of variability can be traced back to …
Foundations of gastrointestinal-based drug delivery and future developments
JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …
administration owing to its convenience for patients, which improves adherence. However …
Novel nano-encapsulated probiotic agents: Encapsulate materials, delivery, and encapsulation systems
C Xu, Q Ban, W Wang, J Hou, Z Jiang - Journal of Controlled Release, 2022 - Elsevier
Gut microbes are closely associated with most human health. When ingested orally,
probiotics can effectively regulate the composition and quantity of human intestinal …
probiotics can effectively regulate the composition and quantity of human intestinal …
RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract
Oral drug delivery of proteins is limited by the degradative environment of the
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …
Oral drug delivery platforms for biomedical applications
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
Harnessing artificial intelligence for the next generation of 3D printed medicines
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …
society, AI is performing tasks with super-human speed and intellect; from the prediction of …
Let's talk about sex: Differences in drug therapy in males and females
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …
man?'Perhaps unintended, such narration extends to the reality of current drug …
[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …
centuries, modern drug discovery and development pipelines challenge conventional …
[HTML][HTML] Oral drug delivery strategies for development of poorly water soluble drugs in paediatric patient population
S Salunke, F O'Brien, DCT Tan, D Harris… - Advanced Drug Delivery …, 2022 - Elsevier
Selecting the appropriate formulation and solubility-enabling technology for poorly water
soluble drugs is an essential element in the development of formulations for paediatric …
soluble drugs is an essential element in the development of formulations for paediatric …
Powering implantable and ingestible electronics
Implantable and ingestible biomedical electronic devices can be useful tools for detecting
physiological and pathophysiological signals, and providing treatments that cannot be done …
physiological and pathophysiological signals, and providing treatments that cannot be done …