[HTML][HTML] Liposomes: structure, biomedical applications, and stability parameters with emphasis on cholesterol
P Nakhaei, R Margiana, DO Bokov… - … in bioengineering and …, 2021 - ncbi.nlm.nih.gov
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …
Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
[HTML][HTML] Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease
TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …
processes related to their structural diversity, and based on this can be broadly classified …
[HTML][HTML] The Fluid—Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than …
GL Nicolson - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2014 - Elsevier
Abstract In 1972 the Fluid—Mosaic Membrane Model of membrane structure was proposed
based on thermodynamic principals of organization of membrane lipids and proteins and …
based on thermodynamic principals of organization of membrane lipids and proteins and …
Phosphatidylethanolamine metabolism in health and disease
E Calzada, O Onguka, SM Claypool - … review of cell and molecular biology, 2016 - Elsevier
Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review
JJ García, L López‐Pingarrón… - Journal of pineal …, 2014 - Wiley Online Library
Free radicals generated within subcellular compartments damage macromolecules which
lead to severe structural changes and functional alterations of cellular organelles. A …
lead to severe structural changes and functional alterations of cellular organelles. A …
Cholesterol modulates the liposome membrane fluidity and permeability for a hydrophilic molecule
The effect of cholesterol (CHOL) content on the permeability and fluidity of
dipalmitoylphosphatidylcholine (DPPC) liposome membrane was investigated. Liposomes …
dipalmitoylphosphatidylcholine (DPPC) liposome membrane was investigated. Liposomes …
Model systems, lipid rafts, and cell membranes
K Simons, WLC Vaz - Annu. Rev. Biophys. Biomol. Struct., 2004 - annualreviews.org
▪ Abstract Views of how cell membranes are organized are presently changing. The lipid
bilayer that constitutes these membranes is no longer understood to be a homogeneous …
bilayer that constitutes these membranes is no longer understood to be a homogeneous …
[HTML][HTML] Lipid rafts: elusive or illusive?
S Munro - Cell, 2003 - cell.com
There has been considerable recent interest in the possibility that the plasma membrane
contains lipid" rafts," microdomains enriched in cholesterol and sphingolipids. It has been …
contains lipid" rafts," microdomains enriched in cholesterol and sphingolipids. It has been …
An overview of liposome lyophilization and its future potential
C Chen, D Han, C Cai, X Tang - Journal of controlled release, 2010 - Elsevier
Lyophilization is a promising approach to ensure the long-term stability of liposomes. After
decades of studies in this field, different lyoprotective mechanisms, such as water …
decades of studies in this field, different lyoprotective mechanisms, such as water …