Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Wearable and implantable devices for drug delivery: Applications and challenges

A Kar, N Ahamad, M Dewani, L Awasthi, R Patil… - Biomaterials, 2022 - Elsevier
Poor adherence to drug dosing schedule is responsible for∼ 50% of hospitalization cases.
Most patients fail to adhere to a strict dosing schedule due to invasive drug administration …

Enhancement strategies for transdermal drug delivery systems: Current trends and applications

D Ramadon, MTC McCrudden, AJ Courtenay… - Drug delivery and …, 2021 - Springer
Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Stimuli-responsive microneedles as a transdermal drug delivery system: a demand-supply strategy

BHJ Gowda, MG Ahmed, A Sahebkar, Y Riadi… - …, 2022 - ACS Publications
Microneedles are one of the most prominent approaches capable of physically disrupting
the stratum corneum without devastating the deeper tissues to deliver both small molecules …

Silk-based flexible electronics and smart wearable Textiles: Progress and beyond

T Xing, A He, Z Huang, Y Luo, Y Zhang, M Wang… - Chemical Engineering …, 2023 - Elsevier
Flexible electronics and smart wearable textiles have been widely used in healthcare
monitoring, flexible sensing, thermal management, protective clothing, energy storage, and …

Core-shell microneedle patch for six-month controlled-release contraceptive delivery

W Li, JY Chen, RN Terry, J Tang, A Romanyuk… - Journal of Controlled …, 2022 - Elsevier
There is a tremendous need for simple-to-administer, long-acting contraception, which can
increase access to improved family planning. Microneedle (MN) patches enable simple self …

Challenges in delivering therapeutic peptides and proteins: A silk-based solution

J Wu, JK Sahoo, Y Li, Q Xu, DL Kaplan - Journal of Controlled Release, 2022 - Elsevier
Peptide-and protein-based therapeutics have drawn significant attention over the past few
decades for the treatment of infectious diseases, genetic disorders, oncology, and many …

The promise of microneedle technologies for drug delivery

RF Donnelly, MR Prausnitz - Drug Delivery and Translational Research, 2024 - Springer
Microneedle (MN) technologies offer the opportunity to improve patient access and target
delivery of drugs and vaccines to specific tissues. When in the form of skin patches, MNs can …

Silk materials at the convergence of science, sustainability, healthcare, and technology

G Guidetti, L d'Amone, T Kim, G Matzeu… - Applied Physics …, 2022 - pubs.aip.org
Over the past few decades, Bombyx mori silk fibroin has become a ubiquitous material for
applications ranging from biomedical devices to optics, electronics, and sensing, while also …