Comorbidities impact a large proportion of patients with chronic obstructive pulmonary
disease (COPD), with over 80% of patients with COPD estimated to have at least one …

Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that
carry significant consequences for patients. Some patients experience frequent …

Rationale: Comorbidities contribute to disease severity and mortality in patients with chronic
obstructive pulmonary disease (COPD). Comorbidities have been studied individually and …

Rationale: Depression is prevalent in patients with chronic obstructive pulmonary disease
(COPD); however, its etiology and relationship to the clinical features of COPD are not well …

Objectives Exacerbations of chronic obstructive pulmonary disease (COPD) are the third
largest cause of emergency hospital admissions in the UK. This systematic literature review …

The term phenotype in the field of COPD is defined as “a single or combination of disease
attributes that describe differences between individuals with COPD as they relate to clinically …

Background The causal association between depression, anxiety, and health-related quality
of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore …

Rationale: Depression and anxiety are significant comorbid and potentially modifiable
conditions in chronic obstructive pulmonary disease (COPD), but their effects on …

Patients with chronic obstructive pulmonary disease (COPD) may suffer from acute episodes
of worsening dyspnea, often associated with increased cough, sputum, and/or sputum …

Extrapulmonary comorbidities are common and significant in chronic obstructive pulmonary
disease (COPD), often contributing to symptoms, exacerbations, hospital admissions and …