Bile acids as metabolic regulators and nutrient sensors
JYL Chiang, JM Ferrell - Annual review of nutrition, 2019 - annualreviews.org
Bile acids facilitate nutrient absorption and are endogenous ligands for nuclear receptors
that regulate lipid and energy metabolism. The brain–gut–liver axis plays an essential role in …
that regulate lipid and energy metabolism. The brain–gut–liver axis plays an essential role in …
[HTML][HTML] The role of vitamin D and vitamin D binding protein in chronic liver diseases
TL Pop, C Sîrbe, G Benţa, A Mititelu… - International journal of …, 2022 - mdpi.com
Vitamin D (calciferol) is a fat-soluble vitamin that has a significant role in phospho-calcium
metabolism, maintaining normal calcium levels and bone health development. The most …
metabolism, maintaining normal calcium levels and bone health development. The most …
Prenatal exposure to perfluoroalkyl substances associated with increased susceptibility to liver injury in children
The severe acute respiratory syndrome coronavirus 2 pandemic has drastically altered all
facets of clinical care and research. Clinical research in hepatology has had a rich tradition …
facets of clinical care and research. Clinical research in hepatology has had a rich tradition …
[HTML][HTML] Biliary Atresia–emerging diagnostic and therapy opportunities
U Lendahl, VCH Lui, PHY Chung, PKH Tam - EBioMedicine, 2021 - thelancet.com
Biliary Atresia is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. In
this review, we describe recent progress in the understanding of liver development with a …
this review, we describe recent progress in the understanding of liver development with a …
[HTML][HTML] Long noncoding RNA H19 contributes to cholangiocyte proliferation and cholestatic liver fibrosis in biliary atresia
Y Xiao, R Liu, X Li, EC Gurley, PB Hylemon, Y Lu… - Hepatology, 2019 - journals.lww.com
Idiosyncratic drug‐induced liver injury (DILI) is a rare, often difficult‐to‐predict adverse
reaction with complex pathomechanisms. However, it is now evident that certain forms of …
reaction with complex pathomechanisms. However, it is now evident that certain forms of …
Diagnostic yield of newborn screening for biliary atresia using direct or conjugated bilirubin measurements
S Harpavat, JA Garcia-Prats, C Anaya, ML Brandt… - Jama, 2020 - jamanetwork.com
Importance Treating biliary atresia in newborns earlier can delay or prevent the need for
liver transplant; however, treatment typically occurs later because biliary atresia is difficult to …
liver transplant; however, treatment typically occurs later because biliary atresia is difficult to …
Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia
SP Amarachintha, R Mourya, H Ayabe, L Yang… - …, 2022 - Wiley Online Library
Abstract Background and Aims Biliary atresia is a severe inflammatory and fibrosing
cholangiopathy of neonates of unknown etiology. The onset of cholestasis at birth implies a …
cholangiopathy of neonates of unknown etiology. The onset of cholestasis at birth implies a …
Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases
Bile duct epithelial cells, also known as cholangiocytes, regulate the composition of bile and
its flow. Acquired, congenital and genetic dysfunctions in these cells give rise to a set of …
its flow. Acquired, congenital and genetic dysfunctions in these cells give rise to a set of …
Cholestatic liver diseases of genetic etiology: Advances and controversies
SH Ibrahim, BM Kamath, KM Loomes, SJ Karpen - Hepatology, 2022 - journals.lww.com
With the application of modern investigative technologies, cholestatic liver diseases of
genetic etiology are increasingly identified as the root cause of previously designated …
genetic etiology are increasingly identified as the root cause of previously designated …
Management of biliary atresia in France 1986 to 2015: long-term results
M Fanna, G Masson, C Capito, M Girard… - Journal of pediatric …, 2019 - journals.lww.com
Objectives: This study analyses the prognosis of biliary atresia (BA) in France since 1986,
when both Kasai operation (KOp) and liver transplantation (LT) became widely available …
when both Kasai operation (KOp) and liver transplantation (LT) became widely available …