Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes that respond to
microbial metabolites. We defined MAIT cell populations in different organs and …

Background Triple-negative breast cancer (TNBC) is a heterogeneous disease that is
characterized by metabolic disruption. Metabolic reprogramming and tumor cell immune …

A simple definition of life is a system that can self-replicate (proliferation) and self-sustain
(metabolism). At the cellular level, metabolism has evolved to drive proliferation, which …

Amino acids, metabolized by host cells as well as commensal gut bacteria, have signaling
effects on host metabolism. Oral supplementation of the essential amino acid histidine has …

Natural killer (NK) cells are critical in protecting the body against infection and cancer. NK
cells can rapidly respond to these threats by directly targeting the infected or transformed …

Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells which
recognize a limited repertoire of ligands presented by the MHC class-I like molecule MR1. In …

Mucosal-Associated Invariant T (MAIT) cells are a population of innate T cells that play a
critical role in host protection against bacterial and viral pathogens. Upon activation, MAIT …

Tuberculosis (TB) is still an urgent global public health problem. Notably, mucosal‐
associated invariant T (MAIT) cells play an important role in early anti‐TB immune response …

Elucidating the relationship between cellular metabolism and T cell function has
substantially advanced our understanding of how T cells are regulated in response to …

Obesity is a chronic progressive disease, which is strongly linked to numerous co-morbid
conditions, and thus is a major global healthcare concern. A major mechanism via which …