The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in …

Changes in extracellular matrix (ECM) components in the lungs are associated with the
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease …

Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …

The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …

Purpose The forced mid-expiratory flow (FEF25-75%) value is a potentially sensitive marker
of obstructive peripheral airflow. We aimed to assess whether FEF25-75% can be an early …

Accumulating evidences demonstrate that long-term exposure to atmospheric fine particles
and air pollutants elevates the risk of chronic obstructive pulmonary disease (COPD) …

Mesenchymal cells are an essential cell type because of their role in tissue support, their
multilineage differentiation capacities and their potential clinical applications. They play a …

CCL13/MCP-4 belongs to the CC chemokine family, which induces chemotaxis in many
immune cells. Despite extensive research into its function in numerous disorders, a thorough …

Cigarette smoke (CS) is the leading risk factor to develop COPD. Therefore, the pathologic
effects of whole CS on the differentiation of primary small airway epithelial cells (SAEC) …

The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …