The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

Abstract Alpha-bisabolol (α-bisabolol), an unsaturated monocyclic sesquiterpene alcohol, is
known as one of the “most-used herbal constituents” in the world. Various therapeutic and …

Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …

Kisspeptin and its G protein-coupled receptor KISS1R play key roles in mammalian
reproduction due to their involvement in the onset of puberty and control of the hypothalamic …

Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

Neurotrophins are a family of functionally and structurally related proteins which play a key
role in the survival, development, and function of neurons in both the central and peripheral …

Background During pregnancy, trophoblast cell invasion needs to be finely controlled.
Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth …

Kisspeptin (KISS1) is encoded by the KISS1 gene and was initially found to be a repressor
of metastasis. Natural mutations in the KISS1 receptor gene (KISS1R) were subsequently …