Profound vasoconstriction in the peripheral circulation is the normal response to conditions
in which the arterial pressure is too low for adequate tissue perfusion, such as acute …

Vasopressin is emerging as a rational therapy for the hemodynamic support of septic shock
and vasodilatory shock due to systemic inflammatory response syndrome. The goal of this …

This document was developed through the collaborative efforts of the Society of Critical Care
Medicine, the American College of Chest Physicians, and the Association of Organ …

Background Vasopressin is commonly used as an adjunct to catecholamines to support
blood pressure in refractory septic shock, but its effect on mortality is unknown. We …

Vasopressin, synthesized in the hypothalamus, is released by increased plasma osmolality,
decreased arterial pressure, and reductions in cardiac volume. Three subtypes of …

Objective: To review all cases of septic shock treated with vasopressin to determine the
effects on hemodynamic and renal function and to document any adverse effects. Setting: A …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

The widespread physiologic changes that follow brain stem death lead to a high incidence
of complications in the donor and jeopardize vital organ function. Strategies for the …

Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …

Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …