[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy

Y Wang, H Qi, Y Liu, C Duan, X Liu, T Xia, D Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

[HTML][HTML] Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

[HTML][HTML] The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

[HTML][HTML] Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements

V Aggarwal, HS Tuli, A Varol, F Thakral, MB Yerer… - Biomolecules, 2019 - mdpi.com
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Role of Nrf2 in aging, Alzheimer's and other neurodegenerative diseases

M George, M Tharakan, J Culberson, AP Reddy… - Ageing Research …, 2022 - Elsevier
Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …

Small-molecule fluorogenic probes for mitochondrial nanoscale imaging

R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

[HTML][HTML] Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

L Vera-Ramirez, SK Vodnala, R Nini, KW Hunter… - Nature …, 2018 - nature.com
Cancer recurrence after initial diagnosis and treatment is a major cause of breast cancer
(BC) mortality, which results from the metastatic outbreak of dormant tumour cells …

[HTML][HTML] Pathomechanisms of paclitaxel-induced peripheral neuropathy

I Klein, HC Lehmann - Toxics, 2021 - mdpi.com
Peripheral neuropathy is one of the most common side effects of chemotherapy, affecting up
to 60% of all cancer patients receiving chemotherapy. Moreover, paclitaxel induces …

[HTML][HTML] Mitochondrial dynamics, ROS, and cell signaling: a blended overview

V Brillo, L Chieregato, L Leanza, S Muccioli, R Costa - Life, 2021 - mdpi.com
Mitochondria are key intracellular organelles involved not only in the metabolic state of the
cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid …