Many biomedical, orthopaedic, and industrial applications are emerging that will benefit from
personalized neuromusculoskeletal models. Applications include refined diagnostics …

Background The ligaments in the knee are prone to injury especially during dynamic
activities. The resulting instability can have a profound impact on a patient's daily activities …

The study objective was to investigate the influence of coronal plane alignment and ligament
properties on total knee replacement (TKR) contact loads during walking. We created a …

Ligaments provide stability to the human knee joint and play an essential role in restraining
motion during daily activities. Compression-tension nonlinearity is a well-known …

Abnormal mechanical loading is essential in the onset and progression of knee
osteoarthritis. Combined musculoskeletal (MS) and finite element (FE) modeling is a typical …

Articular geometry in the knee varies widely among people which has implications for risk of
injury and pathology. The goals of this work were to develop a framework to systematically …

Concurrent multiscale simulation strategies are required in computational biomechanics to
study the interdependence between body scales. However, detailed finite element models …

Background: The way in which force increases in the anterolateral tissues and the lateral
extra-articular tenodesis (LET) tissue to resist internal rotation (IR) of the tibia after anterior …

The objective of this study was to assess the use of an advanced collision detection
algorithm to simulate cartilage contact pressure patterns within dynamic musculoskeletal …

Injuries to the anterior cruciate ligament (ACL) and menisci commonly lead to early onset
osteoarthritis. Treatments that can restore normative cartilage loading patterns may mitigate …