Role of cytokines in the pathogenesis of inflammatory bowel disease
KA Papadakis, SR Targan - Annual review of medicine, 2000 - annualreviews.org
Recent advances in the drug treatment of inflammatory bowel disease (IBD) have paralleled
our understanding of the pathophysiology of ulcerative colitis and Crohn's disease. Several …
our understanding of the pathophysiology of ulcerative colitis and Crohn's disease. Several …
IL-15/IL-15 receptor biology: a guided tour through an expanding universe
V Budagian, E Bulanova, R Paus… - Cytokine & growth factor …, 2006 - Elsevier
The cytokine interleukin-15 (IL-15) has a key role in promoting survival, proliferation and
activation of natural killer (NK) and CD8+ T cells. Despite its functional similarities to IL-2, IL …
activation of natural killer (NK) and CD8+ T cells. Despite its functional similarities to IL-2, IL …
[图书][B] Rosen's Emergency Medicine-Concepts and Clinical Practice E-Book: 2-Volume Set
J Marx, R Hockberger, R Walls - 2013 - books.google.com
Rely on Rosen's Emergency Medicine for the latest answers on every facet of emergency
medicine practice. For decades, this medical reference book has set the standard in …
medicine practice. For decades, this medical reference book has set the standard in …
Prevention of experimental colitis by a selective inhibitor of the immunoproteasome
The proteasome, a multicatalytic protease, is responsible for the degradation of intracellular
proteins. Stimulation of cells with inflammatory cytokines, such as IFN-γ, leads to the …
proteins. Stimulation of cells with inflammatory cytokines, such as IFN-γ, leads to the …
Tumor necrosis factor: biology and therapeutic inhibitors
KA Papadakis, SR Targan - Gastroenterology, 2000 - Elsevier
Tumor necrosis factor (TNF) was originally described as a protein factor capable of killing
tumor cells in vitro and causing hemorrhagic necrosis of transplantable tumors in mice. 1, 2 …
tumor cells in vitro and causing hemorrhagic necrosis of transplantable tumors in mice. 1, 2 …
Prevalence of Bacteroides and Prevotella spp. in ulcerative colitis
K Lucke, S Miehlke, E Jacobs… - Journal of medical …, 2006 - microbiologyresearch.org
The resident bacterial flora of the large intestine has become increasingly recognized as an
essential component in the pathogenesis of ulcerative colitis (UC). However, it is still not …
essential component in the pathogenesis of ulcerative colitis (UC). However, it is still not …
Inflammatory bowel disease: etiology, pathogenesis and current therapy
JK Ko, KK Auyeung - Current pharmaceutical design, 2014 - ingentaconnect.com
Ulcerative colitis (UC) and Crohn's disease (CD) constitute the two major groups of
idiopathic disorders in inflammatory bowel disease (IBD). Environmental factors, genetic …
idiopathic disorders in inflammatory bowel disease (IBD). Environmental factors, genetic …
Impact of sleep disturbances in inflammatory bowel disease
Background: Normal sleep is paramount for a healthy lifestyle and high quality of life. Sleep
modulates the immune system and thus affects the course of several chronic inflammatory …
modulates the immune system and thus affects the course of several chronic inflammatory …
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease
MM Kosiewicz, CC Nast, A Krishnan… - The Journal of …, 2001 - Am Soc Clin Investig
We describe here the immunologic characterization of a new mouse strain, SAMP1/Yit,
which spontaneously develops a chronic intestinal inflammation localized to the terminal …
which spontaneously develops a chronic intestinal inflammation localized to the terminal …
Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients
T Ali, MF Madhoun, WC Orr… - Inflammatory bowel …, 2013 - academic.oup.com
Purpose Poor sleep quality is associated with adverse health consequences. Sleep
disturbances can impact the immune function and process of inflammation. The relationship …
disturbances can impact the immune function and process of inflammation. The relationship …