Inflammatory bowel disease in children 5 years of age and younger

P Mamula, GW Telega, JE Markowitz… - Official journal of the …, 2002 - journals.lww.com
OBJECTIVES: Clinicians are becoming increasingly aware that inflammatory bowel disease
(IBD) can affect all age groups, although it has not been well described in infants and young …

CCR9–Positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease

KA Papadakis, J Prehn, ST Moreno, L Cheng… - Gastroenterology, 2001 - Elsevier
Background & Aims: Thymus-expressed chemokine (TECK) or CCL25) is selectively
expressed in the small bowel (SB), where lamina propria lymphocytes (LPL) and …

IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine production

Z Liu, K Geboes, S Colpaert, GR D'Haens… - The Journal of …, 2000 - journals.aai.org
IL-15 shares biological activities but no significant sequence homology with IL-2. It induces T
cell recruitment to sites of inflammation, T cell proliferation, and cytokine production and …

Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice

Y Araki, KI Mukaisyo, H Sugihara… - Oncology …, 2010 - spandidos-publications.com
The pathogenic mechanisms responsible for inflammatory bowel disease, especially
ulcerative colitis (UC), are poorly understood. In animal models, the oral administration of …

Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice

RC Burns, J Rivera-Nieves, CA Moskaluk… - Gastroenterology, 2001 - Elsevier
BACKGROUND & AIMS:: Integrins (α4 and β2) and their endothelial ligands vascular cell
adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) play key …

Low-dose naltrexone therapy improves active Crohn's disease

JP Smith, H Stock, S Bingaman, D Mauger… - Official journal of the …, 2007 - journals.lww.com
OBJECTIVES Endogenous opioids and opioid antagonists have been shown to play a role
in healing and repair of tissues. In an open-labeled pilot prospective trial, the safety and …

Immune response to influenza vaccine in pediatric patients with inflammatory bowel disease

P Mamula, JE Markowitz, DA Piccoli, A Klimov… - Clinical …, 2007 - Elsevier
Background & Aims: The aim of this study was to compare response to inactivated influenza
vaccine in healthy children and pediatric patients with inflammatory bowel disease (IBD) …

[HTML][HTML] Updated review on immune factors in pathogenesis of Crohn's disease

N Li, RH Shi - World Journal of Gastroenterology, 2018 - ncbi.nlm.nih.gov
Although the incidence of Crohn's disease (CD) in China is not as high as that in European
and American countries, there has been a clear increasing trend in recent years. Little is …

Human leukocyte subpopulations from inflamed gut bind to joint vasculature using distinct sets of adhesion molecules

M Salmi, S Jalkanen - The Journal of Immunology, 2001 - journals.aai.org
Reactive arthritis can be triggered by inflammatory bowel diseases. We hypothesized that
migration of mucosal immune cells from inflamed gut to joints could contribute to the …

Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats

A Vetuschi, G Latella, R Sferra, R Caprilli… - Digestive diseases and …, 2002 - Springer
We have evaluated morphologic alterations and epithelial cell apoptosis and proliferation of
colonic mucosa in the acute and chronic phases of DSS-induced colitis. Colitis was induced …