Integrated metabolomics and network pharmacology strategy for ascertaining the quality marker of flavonoids for Sophora flavescens
L Chen, X Huang, H Wang, J Shao, Y Luo… - … of Pharmaceutical and …, 2020 - Elsevier
Abstract Traditional Chinese medicines (TCMs) have been widely used in Asian countries
for thousands of years due to their supreme quality and good clinical efficacy. However, the …
for thousands of years due to their supreme quality and good clinical efficacy. However, the …
An integrated metabolism in vivo analysis and network pharmacology in UC rats reveal anti-ulcerative colitis effects from Sophora flavescens EtOAc extract
L Chen, J Shao, Y Luo, L Zhao, K Zhao, Y Gao… - … of Pharmaceutical and …, 2020 - Elsevier
Ulcerative colitis (UC), an immune system disease, is characterized by long duration and
easy relapse. Sophora flavescens (S. flavescens), also named “Kushen”, is a traditional …
easy relapse. Sophora flavescens (S. flavescens), also named “Kushen”, is a traditional …
Recent advances on drug analyses using ultra performance liquid chromatographic techniques and their application to the biological samples
S Kurbanoglu, O Karsavurdan… - Current Analytical …, 2019 - ingentaconnect.com
Introduction: Ultra-Performance Liquid Chromatographic (UPLC) method enables analyst to
establish an analysis at higher pressure than High Performance Liquid Chromatographic …
establish an analysis at higher pressure than High Performance Liquid Chromatographic …
[PDF][PDF] In vitro and in vivo human gastric cancer inhibition by Trifolirhizin is facilitated via autophagy, mitochondrial mediated programmed cell death, G2/M phase cell …
K Zhang, W Liu, Z Qu, Q Liu, J Chen, R Tao, Y Deng… - J BUON, 2019 - jbuon.com
Purpose: To investigate the anticancer effects of Trifolirhizin in SNU-5 human gastric cancer
cells along with evaluation of its effects on autophagy, apoptosis, cell cycle phase …
cells along with evaluation of its effects on autophagy, apoptosis, cell cycle phase …
Trifolirhizin relieves renal injury in a diabetic nephropathy model by inducing autophagy and inhibiting oxidative stress through the regulation of PI3K/AKT/mTOR …
Y Xin, X Xu, X Yang, Y Chen, D Zhu - Tropical Journal of Pharmaceutical …, 2022 - ajol.info
Purpose: To evaluate the effects of trifolirhizin on diabetic nephropathy (DN), and the
mechanism of action. Methods: Male db/db mice (8 weeks, n= 24) and age-matched control …
mechanism of action. Methods: Male db/db mice (8 weeks, n= 24) and age-matched control …
Determining concentrations of icotinib in plasma of rat by UPLC method with ultraviolet detection: Applications for pharmacokinetic studies
J Xiong, H Ye, Y Lin, J Yang, D Chen… - Current …, 2017 - ingentaconnect.com
Introduction: In our research, a rapid, selective and sensitive analytical method based on
ultra-performance liquid chromatography (UPLC) was developed and validated for the …
ultra-performance liquid chromatography (UPLC) was developed and validated for the …
[HTML][HTML] Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration
L Chen, Y Zhang - Revista da Associação Médica Brasileira, 2019 - SciELO Brasil
Mirabegron is a kind of β3 adrenergic receptor agonist which is an effective drug for the
treatment of overactive bladder. In this research, a UPLC–MS/MS method is developed and …
treatment of overactive bladder. In this research, a UPLC–MS/MS method is developed and …
[HTML][HTML] Development and validation of a UPLC-MS/MS method for the quantification of acetaminophen in human plasma and its application to pharmacokinetic …
J Cha, BK Kim, MR Gwon, J Lee, B Ohk… - Translational and …, 2016 - tcpharm.org
We developed an ultra-performance liquid chromatography-tandem mass spectrometry
(UPLC-MS/MS) method for the determination of acetaminophen concentration in human …
(UPLC-MS/MS) method for the determination of acetaminophen concentration in human …
Fully validated ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of Fimasartan in human plasma
JY Hyun, HJ Kim, MR Gwon, HW Lee, SJ Seong… - Analytical …, 2015 - Springer
Fimasartan is a novel angiotensin II receptor blocker with strong anti-hypertensive activity. In
this study, a more rapid and sensitive ultra-performance liquid chromatography–tandem …
this study, a more rapid and sensitive ultra-performance liquid chromatography–tandem …
Determination of isavuconazole in rat plasma by UPLC-MS/MS: application to a pharmacokinetic study
B Liang, L Yuan, Y Zhan, M Jin, E Gu, G Hu - Analytical methods, 2016 - pubs.rsc.org
Isavuconazole (ISA) is a new generation, broad-spectrum triazole with efficacy against
invasive fungal diseases including aspergillosis and mucormycosis. In this study, a rapid …
invasive fungal diseases including aspergillosis and mucormycosis. In this study, a rapid …