This paper reviews a novel hypothesis about the functions of slow wave sleep—the synaptic
homeostasis hypothesis. According to the hypothesis, plastic processes occurring during …

Recent studies have shown that frontoparietal cortices and interconnecting regions in the
basal ganglia and the cerebellum are related to motor skill learning. We propose that motor …

During much of sleep, the cerebral cortex is rippled by slow waves, which appear in the
electroencephalogram as oscillations between 0.5 and 4.5 Hz. Slow waves are regulated as …

We have investigated a potential mechanism by which a diet, similar in composition to the
typical diet of most industrialized western societies rich in saturated fat and refined sugar …

It has long been hypothesized that morphological and numerical alterations in dendritic
spines underlie long-term structural encoding of experiences. Here we investigate the …

For over 100 years a central assumption in the field of neuroscience has been that new
neurons are not added to the adult mammalian brain. This perspective examines the origins …

Neuronal connections and cortical maps are continuously remodeled by our experience.
Knowledge of the potential capabilityof the brain to compensate for lesions is a prerequisite …

In the current article, we provide a critical review of the extant literature that has focused on
environmental influences on cognitive and brain plasticity over the adult life span. The …

From biology to culture to the new new economy, the buzzword on everyone's lips is"
meme." How do animals learn things? How does human culture evolve? How does viral …

Although it is believed that little recovery occurs after adult mammalian spinal cord injury, in
fact significant spontaneous functional improvement commonly occurs after spinal cord …