[HTML][HTML] Monoclonal antibodies in the treatment of diffuse Large b-cell lymphoma: Moving beyond rituximab

SG Papageorgiou, TP Thomopoulos, A Liaskas… - Cancers, 2022 - mdpi.com
Simple Summary Diffuse large B-cell lymphoma (DLBCL) is the most common high-grade
non-Hodgkin lymphoma. The current treatment combining the anti-CD20 monoclonal …

A phase 1b study of AFM13 in combination with pembrolizumab in patients with relapsed or refractory Hodgkin lymphoma

NL Bartlett, AF Herrera… - Blood, The Journal …, 2020 - ashpublications.org
In relapsed/refractory Hodgkin lymphoma (R/R HL), immunotherapies such as the anti-
programmed death-1 inhibitor pembrolizumab have demonstrated efficacy as monotherapy …

Optimizing outcomes in relapsed/refractory Hodgkin lymphoma: a review of current and forthcoming therapeutic strategies

TP Vassilakopoulos… - Therapeutic …, 2020 - journals.sagepub.com
The outcome of patients with relapsed/refractory classical Hodgkin lymphoma (rr-cHL) has
improved considerably in recent years owing to the approval of highly active novel agents …

[HTML][HTML] The third-generation anti-CD30 CAR T-cells specifically homing to the tumor and mediating powerful antitumor activity

S Zhang, C Gu, L Huang, H Wu, J Shi, Z Zhang… - Scientific reports, 2022 - nature.com
CAR T-cell therapy is well tolerated and effective in patients with Hodgkin lymphoma (HL)
and anaplastic large cell lymphoma (ALCL). However, even second-generation anti-CD30 …

[HTML][HTML] Dissecting tumor-immune microenvironment in breast cancer at a spatial and multiplex resolution

E Tzoras, I Zerdes, N Tsiknakis, GC Manikis… - Cancers, 2022 - mdpi.com
Simple Summary The evaluation of breast cancer immune microenvironment has been
increasingly used in clinical practice, either by counting tumor infiltrating lymphocytes or …

[HTML][HTML] The Role of mTOR in B Cell Lymphoid Malignancies: Biologic and Therapeutic Aspects

EA Karatrasoglou, M Dimou, A Piperidou… - International Journal of …, 2023 - mdpi.com
Non-Hodgkin lymphoma's (NHL) incidence is rising over time, and B cell lymphomas
comprise the majority of lymphomas. The phosphoinositide 3-kinase (PI3K)/v-akt murine …

[HTML][HTML] The value of FDG PET/CT imaging in outcome prediction and response assessment of lymphoma patients treated with immunotherapy: a meta-analysis and …

Z Kiamanesh, N Ayati, R Sadeghi, E Hawkes… - European journal of …, 2022 - Springer
Purpose Treatment strategies of lymphoid malignancies have been revolutionized by
immunotherapy. Because of the inherent property of Hodgkin lymphoma and some subtypes …

An international real-world analysis of relapsed/refractory lymphoma occurring during pregnancy

F Farooq, JS Brandt, E Cardonick… - Blood …, 2023 - ashpublications.org
Cancer complicates~ 1 in 1000 pregnancies, which translates into~ 4000 cases annually in
the United States. 1 Lymphoma is the fourth most common malignancy and the most …

[HTML][HTML] Classical Hodgkin's lymphoma in the era of immune checkpoint inhibition

V De Re, L Caggiari, O Repetto, L Mussolin… - Journal of clinical …, 2019 - mdpi.com
The ligation of programmed cell death 1 (PD-1) with programmed cell death ligand PD-L
activates the immune checkpoint leading to T-cell dysfunction, exhaustion, and tolerance …

Signaling alterations caused by drugs and autophagy

P Dent, L Booth, A Poklepovic, JF Hancock - Cellular Signalling, 2019 - Elsevier
Autophagy is an evolutionary conserved process that recycles cellular materials in times of
nutrient restriction to maintain viability. In cancer therapeutics, the role of autophagy in …