Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Broad interest in developing new hemostatic technologies arises from unmet needs in
mitigating uncontrolled hemorrhage in emergency, surgical, and battlefield settings …

Abstract These European Resuscitation Council (ERC) Cardiac Arrest in Special
Circumstances guidelines are based on the 2020 International Consensus on …

METHODS The recommendations were developed as a synthesis and update of evidence
from the literature. They are based on the FIGO Safe Motherhood and Newborn Health …

Background Time to treatment matters in traumatic haemorrhage but the optimal prehospital
use of blood in major trauma remains uncertain. We investigated whether use of packed red …

Importance Tranexamic acid (TXA) is an efficient antifibrinolytic agent; however, concerns
remain about the potential adverse effects, particularly vascular occlusive events, that may …

Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Blood loss by hemorrhaging wounds accounts for over one-third of∼ 5 million trauma
fatalities worldwide every year. If not controlled in a timely manner, exsanguination can take …

Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

Abstract The World Health Organization (WHO) has declared coronavirus disease 2019
(COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 …