Neutrophils activated during acute lung injury (ALI) form neutrophil extracellular traps
(NETs) to capture pathogens. However, excessive NETs can cause severe inflammatory …

The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Background Macrophage polarization and reprogramming in the lung play a critical role in
the initiation, development and progression of acute lung injury (ALI). Regulating the …

Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are
severe inflammatory lung diseases. Methylprednisolone (MP) is a common drug against …

Macrophages are major upstream regulators of the inflammatory response to implanted
biomaterials. Sequential functions of distinct macrophage phenotypes are essential to the …

Acute respiratory distress syndrome is an often fatal disease that develops after acute lung
injury and trauma. How released tissue damage signals, or alarmins, orchestrate early …

Efferocytosis of apoptotic neutrophils (PMNs) by alveolar macrophages (AMФs) is vital for
resolution of inflammation and tissue injury. Here, we investigated the role of AMФ …

Acute respiratory distress syndrome is an inflammatory disease characterized by dysfunction
of pulmonary epithelial and capillary endothelial cells, infiltration of alveolar macrophages …

Cytoskeleton proteins have been reported to be involved in the host antiviral immune
responses. However, how cytoskeleton proteins regulate host antiviral immune responses is …

The notion that neutrophils exist as a homogeneous population is being replaced with the
knowledge that neutrophils adopt different functional states. Neutrophils can have a pro …