Inflammation‐modulating nanoparticles for pneumonia therapy

W Muhammad, Z Zhai, S Wang… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Pneumonia is a common but serious infectious disease, and is the sixth leading cause for
death. The foreign pathogens such as viruses, fungi, and bacteria establish an inflammation …

M2A and M2C macrophage subsets ameliorate inflammation and fibroproliferation in acute lung injury through interleukin 10 pathway

L Tang, H Zhang, C Wang, H Li, Q Zhang, J Bai - Shock, 2017 - journals.lww.com
The role of M 2 macrophages in the resolution and fibroproliferation of acute lung injury (ALI)
is poorly understood. In this study, we investigated the effects of two M 2 macrophage …

[HTML][HTML] Depression of lncRNA MINCR antagonizes LPS-evoked acute injury and inflammatory response via miR-146b-5p and the TRAF6-NFkB signaling

W Gao, Y Zhang - Molecular Medicine, 2021 - Springer
Background Inflammation plays an important role in the development of acute lung injury
(ALI) and acute respiratory distress syndrome (ARDS). The long non-coding RNA (lncRNA) …

[HTML][HTML] Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in …

RY Mahida, S Lax, CR Bassford, A Scott… - Frontiers in …, 2023 - frontiersin.org
Background Acute Respiratory Distress Syndrome (ARDS) is a devastating pulmonary
inflammatory disorder, commonly precipitated by sepsis. Glucocorticoids are …

Correlations of IL-17 and NF-κB gene polymorphisms with susceptibility and prognosis in acute respiratory distress syndrome in a chinese population

M Xie, B Cheng, Y Ding, C Wang, J Chen - Bioscience reports, 2019 - portlandpress.com
The present study was performed to investigate the association between interleukin-17 (IL-
17) and nuclear factor κB (NF-κB) gene polymorphisms and the risk and prognosis of acute …

Inflammatory processes during acute respiratory distress syndrome: a complex system

LK Reiss, A Schuppert, S Uhlig - Current opinion in critical care, 2018 - journals.lww.com
Inflammatory processes during acute respiratory distress syn... : Current Opinion in Critical
Care Inflammatory processes during acute respiratory distress syndrome: a complex system …

[HTML][HTML] Scrub Typhus Pathogenesis: Innate Immune Response and Lung Injury During Orientia tsutsugamushi Infection

B Trent, J Fisher, L Soong - Frontiers in Microbiology, 2019 - frontiersin.org
Scrub typhus is an understudied, potentially lethal disease caused by infection with Orientia
tsutsugamushi. Despite causing an estimated 1 million cases per year and an increasing …

Immunomodulatory properties of captopril, an ACE inhibitor, on LPS-induced lung inflammation and fibrosis as well as oxidative stress

J Boskabadi, VR Askari, M Hosseini… - …, 2019 - Springer
Background The role of angiotensin converting enzyme inhibitors on the inflammation
process has been demonstrated previously. In the present study, the effects of captopril on …

GTS-21 reduces inflammation in acute lung injury by regulating M1 polarization and function of alveolar macrophages

J Wang, R Li, Z Peng, W Zhou, B Hu, X Rao, X Yang… - Shock, 2019 - journals.lww.com
Background: Acute lung injury (ALI) is a severe outcome of sepsis. Alveolar macrophages
(AMs) play key roles in defense, resolution in ALI. The polarization of AMs is dependent on …

CircN4bp1 facilitates sepsis‐induced acute respiratory distress syndrome through mediating macrophage polarization via the miR‐138‐5p/EZH2 Axis

D Zhao, C Wang, X Liu, N Liu, S Zhuang… - Mediators of …, 2021 - Wiley Online Library
We recently reported the differential circRNA expression patterns of the pulmonary
macrophages in sepsis‐induced acute respiratory distress syndrome (ARDS) mice model by …