Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

[HTML][HTML] Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

Role of particle size in translational research of nanomedicines for successful drug delivery: Discrepancies and inadequacies

HW Chan, S Chow, X Zhang, PCL Kwok… - Journal of Pharmaceutical …, 2023 - Elsevier
Despite significant research progress in substantiating the therapeutic merits of
nanomedicines and the emergence of sophisticated nanotechnologies, the translation of this …

[HTML][HTML] Nano-formulations for pulmonary delivery: Past, present, and future perspectives

S Peng, W Wang, R Zhang, C Wu, X Pan, Z Huang - Pharmaceutics, 2024 - mdpi.com
With the development of nanotechnology and confronting the problems of traditional
pharmaceutical formulations in treating lung diseases, inhalable nano-formulations have …

Building respirable powder architectures: utilizing polysaccharides for precise control of particle morphology for enhanced pulmonary drug delivery

K Kadota, H Uchiyama, T Kämäräinen… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Dry powder inhaler (DPI) formulations are gaining attention as universal
formulations with applications in a diverse range of drug formulations. The practical …

Supercritical antisolvent-fluidized bed for the preparation of dry powder inhaler for pulmonary delivery of nanomedicine

Z Ma, X Zhang, L Ping, Z Zhong, X Zhang… - International Journal of …, 2023 - Elsevier
The supercritical antisolvent-fluidized bed coating process (SAS-FB) shows great potential
as a technique to manufacture dry powder inhaler (DPI) that incorporate nanodrugs onto …

Nano-based carriers for pulmonary drug delivery: A review on the available drug delivery applications and toxicity issues

PI Siafaka, EÖ Bülbül, AN Miliotou, ID Karantas… - Journal of Drug Delivery …, 2024 - Elsevier
In the last decade, nanocarriers have been widely used to target specific organs and
disorders of any kind. Nonetheless, the commercialization of nanocarriers for many …

Biocompatible biodegradable polymeric nanocarriers in dry powder inhalers (DPIs) for pulmonary inhalation delivery

D Encinas-Basurto, BB Eedara… - Journal of Pharmaceutical …, 2024 - Springer
Background Pulmonary drug delivery is an efficient way to deliver drugs directly to the site of
action ie, lungs or to the blood circulation with minimum systemic effects. Recent emergence …

[HTML][HTML] The challenges to develop antibody-conjugated nanomedicine products

L Hui, W Chen, M Najlah - Nano TransMed, 2023 - Elsevier
Nanomedicine becomes a key player especially as next generation medicine. Antibody-
conjugated nanomedicine could significantly upgrade the treatment and expand application …

Lipid polymer hybrid nanoparticles against lung cancer and their application as inhalable formulation

SN Kassaee, D Richard, GA Ayoko, N Islam - Nanomedicine, 2024 - Taylor & Francis
Lung cancer is a leading cause of global cancer mortality, often treated with
chemotherapeutic agents. However, conventional approaches such as oral or intravenous …