Monoterpenoid indole alkaloid dimers from the Melodinus axillaris induce G2/M phase arrest and apoptosis via p38 MAPK activation in HCT116 cells

K Du, X Li, C Zheng, L Lai, M Shen, Y Wang… - Bioorganic Chemistry, 2023 - Elsevier
Four monoterpenoid indole alkaloid dimers (MIADs), axidimins AD (1–4), which possesses
unprecedented apidosperma-aspidosperma-type skeletons, along with twelve known MIAs …

Unlocking the hidden potential: Enhancing the utilization of stems and leaves through metabolite analysis and toxicity assessment of various parts of Aconitum …

Y Zhou, C Qu, H Yan, T Chu, J Wu, Q Kang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Aconitum carmichaelii is widely used in traditional
Chinese medicine clinics as a bulk medicinal material. It has been used in China for more …

An Overview of Chemistry and Bioactivity of Non-diterpenoid Alkaloids in the Genera Aconitum and Delphinium (Ranunculaceae)

T Yin, H Jiang - Current Organic Chemistry, 2023 - ingentaconnect.com
Tribe Delphineae in the family Ranunculaceae is composed of the genera Aconitum and
Delphinium and is a resource plant group with important medicinal value. Alkaloids are the …

Selective Activity Against Amastigote Forms of Trypanosoma cruzi and Leishmania infantum of Diastereomeric Dicentrine N‐oxides

DC Tristão, H Barbosa… - Chemistry & …, 2024 - Wiley Online Library
As part of our continuous research for the discovery of bioactive compounds against
Trypanosoma cruzi and Leishmania infantum, the alkaloid (6aS)‐dicentrine (1) was oxidized …

Antiviral and cytotoxic indole diterpenoids from the antarctic sponge-derived fungus Aspergillus candidus HDN15-152

B Tang, R Zhang, F Zhang, T Zhu, Q Che… - Natural Product …, 2024 - Taylor & Francis
One new indole diterpenoid, ascandinine T (1), and three known analogues (2–4) were
isolated from an Antarctic sponge-derived fungus Aspergillus candidus HDN15-152. The …

Two new anthranilamides with chemotaxonomic value from Delphinium tatsienense

X Tu, J Chen, X Liu, J He - Biochemical Systematics and Ecology, 2024 - Elsevier
Delphinium L.(Ranunculaceae) is a taxonomically complex genus composed of
approximately 365 species of perennial herbs. Chemical taxonomy is highly important for …