Cirrhosis is a form of liver fibrosis resulting from chronic hepatitis and caused by various liver
diseases, including viral hepatitis, alcoholic liver damage, nonalcoholic steatohepatitis, and …

Tumor-associated macrophages (TAM) play pivotal roles in tumor progression and
metastasis, but the contribution and regulation of different macrophage populations remain …

Liver fibrosis is a life-threatening disease, with challenging morbidity and mortality for
healthcare systems worldwide. It imparts an enormous economic burden to societies …

Liver fibrosis affects millions of people worldwide and is rising vastly over the past decades.
With no viable therapies available, liver transplantation is the only curative treatment for …

Macrophages are important players in the immune system that sense various tissue
challenges and trigger inflammation. Tissue injuries are followed by inflammation, which is …

Intestinal fibrosis and stricture formation is an aggressive complication of Crohns disease
(CD), linked to increased morbidity and costs. The present study investigates the …

Aging leads to a high burden on society, both medically and economically. Cellular
senescence plays an essential role in the initiation of aging and age-related diseases …

Helicobacter pylori (H. pylori) infects approximately 50% of the world population. The
multiple gastrointestinal and extra-gastrointestinal diseases caused by H. pylori infection …

Nonalcoholic fatty liver disease (NAFLD) is a global health concern associated with
significant morbidity and mortality. NAFLD is a spectrum of diseases originating from simple …

Long-term liver injuries lead to hepatic fibrosis, often progressing into cirrhosis, liver failure,
portal hypertension, and hepatocellular carcinoma. There is currently no effective therapy …