Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …

Tuberculosis, caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb), is the
leading cause of death from an infectious disease, with a mortality rate of over a million …

Cardiolipin, the signature phospholipid of mitochondria, is a lipid dimer that is important for a
diverse range of mitochondrial activities beyond the process of ATP production. Thus not …

Over the past 15 years, investigators have shown that T lymphocytes can recognize not only
peptides in the context of MHC class I and class II molecules but also foreign and self-lipids …

Invariant natural killer T cells (i NKT cells) have a prominent role during infection and other
inflammatory processes, and these cells can be activated through their T cell antigen …

In most adult humans, hepatitis B is a self-limiting disease leading to life-long protective
immunity, which is the consequence of a robust adaptive immune response occurring weeks …

The development and maturation of semi-invariant natural killer T cells (i NKT cells) rely on
the recognition of self antigens presented by CD1d restriction molecules in thymus. The …

CD1-and MHC-related molecule-1 (MR1)-restricted T lymphocytes recognize nonpeptidic
antigens, such as lipids and small metabolites, and account for a major fraction of circulating …

Natural killer T (NKT) cells are a subset of T lymphocytes with potent immunoregulatory
properties. Recognition of self-antigens presented by CD1d molecules is an important route …

NKT cells recognize lipid Ags presented by a class I MHC-like molecule CD1d, a member of
the CD1 family. Although most initial studies on NKT cells focused on a subset with semi …