Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - Am Soc Microbiol
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …

[HTML][HTML] Wound antiseptics and European guidelines for antiseptic application in wound treatment

ZŁ Babalska, M Korbecka-Paczkowska, TM Karpiński - Pharmaceuticals, 2021 - mdpi.com
Issues arising in wound healing are very common, and chronic wound infections affect
approximately 1.5% of the population. The main substances used in wound washing …

The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility

VN Kos, M Déraspe, RE McLaughlin… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Many clinical isolates of Pseudomonas aeruginosa cause infections that are difficult to
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …

Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa

A van Belkum, LB Soriaga, MC LaFave, S Akella… - MBio, 2015 - Am Soc Microbiol
Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and
extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for …

[HTML][HTML] Bacterial genome sequencing in clinical microbiology: a pathogen-oriented review

F Tagini, G Greub - European journal of clinical microbiology & infectious …, 2017 - Springer
In recent years, whole-genome sequencing (WGS) has been perceived as a technology with
the potential to revolutionise clinical microbiology. Herein, we reviewed the literature on the …

Prevention and control of multi-drug-resistant Gram-negative bacteria: recommendations from a Joint Working Party

APR Wilson, DM Livermore… - Journal of …, 2016 - journalofhospitalinfection.com
1. Executive summary Multi-drug-resistant (MDR) Gram-negative bacterial infections have
become prevalent in some European countries. Moreover, increased use of broad-spectrum …

[HTML][HTML] Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis

CL Gorrie, AG Da Silva, DJ Ingle, C Higgs… - The Lancet …, 2021 - thelancet.com
Background Pairwise single nucleotide polymorphisms (SNPs) are a cornerstone of
genomic approaches to the inference of transmission of multidrug-resistant (MDR) …

[HTML][HTML] Whole-genome sequencing targets drug-resistant bacterial infections

NV Punina, NM Makridakis, MA Remnev, AF Topunov - Human genomics, 2015 - Springer
During the past two decades, the technological progress of whole-genome sequencing
(WGS) had changed the fields of Environmental Microbiology and Biotechnology, and …

[HTML][HTML] Diversity and Distribution of Resistance Markers in Pseudomonas aeruginosa International High-Risk Clones

B Kocsis, D Gulyás, D Szabó - Microorganisms, 2021 - mdpi.com
Pseudomonas aeruginosa high-risk clones are disseminated worldwide and they are
common causative agents of hospital-acquired infections. In this review, we will summarize …