Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Exposure to phthalates and female reproductive health: A literature review

CG Basso, AT de Araújo-Ramos… - Reproductive …, 2022 - Elsevier
Endocrine-disrupting chemicals (EDCs) are exogenous compounds that have been known
for their ability to interfere with the action of hormones and affect endocrine pathways …

Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation

T Iizuka, P Yin, A Zuberi, S Kujawa… - Proceedings of the …, 2022 - National Acad Sciences
Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15
to 30% of reproductive-age women. Epidemiological studies consistently indicate a …

Uterine fibroids and diet

A Tinelli, M Vinciguerra, A Malvasi, M Andjić… - International journal of …, 2021 - mdpi.com
Uterine myomas or fibroids are the most common benign female tumors of the reproductive
organs, associated with significant morbidity and quality of life impairment. Several …

The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis

MV Bariani, R Rangaswamy, H Siblini… - Current Opinion in …, 2020 - journals.lww.com
While research on EDCs and fibroids is still evolving, recent evidence suggests EDC
exposures may contribute to fibroid risk and progression. Further research is needed to …

Integrating intersectionality into the exposome paradigm: a novel approach to racial inequities in uterine fibroids

AR Zota, BN VanNoy - American Journal of Public Health, 2021 - ajph.aphapublications.org
Intersectionality is a critical theoretical framework that emphasizes the influence of
intersecting systems of oppression on the lived experiences of people marginalized by …

Developmental reprogramming of myometrial stem cells by endocrine disruptor linking to risk of uterine fibroids

Q Yang, M Ali, LS Treviño, A Mas… - Cellular and Molecular Life …, 2023 - Springer
Background The stage, when tissues and organs are growing, is very vulnerable to
environmental influences, but it's not clear how exposure during this time causes changes to …

Update on the role and regulatory mechanism of extracellular matrix in the pathogenesis of uterine fibroids

Q Yang, A Al-Hendy - International Journal of Molecular Sciences, 2023 - mdpi.com
Uterine fibroids (UFs), also known as leiomyomas, are benign tumors of the myometrium
affecting over 70% of women worldwide, particularly women of color. Although benign, UFs …

[HTML][HTML] Integrating-omics approaches into population-based studies of endocrine disrupting chemicals: A scoping review

L Maitre, P Jedynak, M Gallego, L Ciaran… - Environmental …, 2023 - Elsevier
Health effects of endocrine disrupting chemicals (EDCs) are challenging to detect in the
general population. Omics technologies become increasingly common to identify early …

A view on uterine leiomyoma genesis through the prism of genetic, epigenetic and cellular heterogeneity

AS Koltsova, OA Efimova, AA Pendina - International Journal of …, 2023 - mdpi.com
Uterine leiomyomas (ULs), frequent benign tumours of the female reproductive tract, are
associated with a range of symptoms and significant morbidity. Despite extensive research …