[HTML][HTML] Dual role of indoles derived from intestinal microbiota on human health

X Ye, H Li, K Anjum, X Zhong, S Miao, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Endogenous indole and its derivatives (indoles), considered as promising N-substituted
heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and …

[HTML][HTML] The current and future perspectives of postbiotics

B Liang, D Xing - Probiotics and Antimicrobial Proteins, 2023 - Springer
With the emphasis on intestinal health, probiotics have exploded into a vast market potential.
However, new scientific evidence points out that the beneficial health benefits of probiotics …

[HTML][HTML] Gut microbiome-produced metabolites in pigs: A review on their biological functions and the influence of probiotics

R Vasquez, JK Oh, JH Song… - Journal of Animal Science …, 2022 - ncbi.nlm.nih.gov
The gastrointestinal tract is a complex ecosystem that contains a large number of
microorganisms with different metabolic capacities. Modulation of the gut microbiome can …

Psoriasis: Interplay between dysbiosis and host immune system

B Kapoor, M Gulati, P Rani, R Gupta - Autoimmunity reviews, 2022 - Elsevier
With advancement in human microbiome research, an increasing number of scientific
evidences have endorsed the key role of both gut and skin microbiota in the pathogenesis of …

[HTML][HTML] Interactions between tryptophan metabolism, the gut microbiome and the immune system as potential drivers of non-alcoholic fatty liver disease (NAFLD) and …

C Teunis, M Nieuwdorp, N Hanssen - Metabolites, 2022 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing and therefore is its
burden of disease as NALFD is a risk factor for cirrhosis and is associated with other …

[HTML][HTML] Food-derived uremic toxins in chronic kidney disease

M Lauriola, R Farré, P Evenepoel, SA Overbeek… - Toxins, 2023 - mdpi.com
Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to
the average population, and this is partially due to the plasma accumulation of solutes …

[HTML][HTML] Microbial-derived tryptophan catabolites, kidney disease and gut inflammation

AM Madella, J Van Bergenhenegouwen, J Garssen… - Toxins, 2022 - mdpi.com
Uremic metabolites, molecules either produced by the host or from the microbiota population
existing in the gastrointestinal tract that gets excreted by the kidneys into urine, have …

Lactic acid fermentation of goji berries (Lycium barbarum) prevents acute alcohol liver injury and modulates gut microbiota and metabolites in mice

W Duan, L Zhou, Y Ren, F Liu, Y Xue, FZ Wang… - Food & Function, 2024 - pubs.rsc.org
Juice fermented with lactic acid bacteria (LAB) has received attention due to its health
benefits, such as antioxidant and anti-inflammatory. Previous research on LAB-fermented …

Host–microbiome orchestration of the sulfated metabolome

GD D'Agostino, SN Chaudhari, AS Devlin - Nature Chemical Biology, 2024 - nature.com
Recent studies have demonstrated that metabolites produced by commensal bacteria
causally influence health and disease. The sulfated metabolome is one class of molecules …

Impact of high-fiber or high-protein diet on the capacity of human gut microbiota to produce tryptophan catabolites

Z Huang, J Boekhorst, V Fogliano… - Journal of Agricultural …, 2023 - ACS Publications
This study investigated the effect of high-fiber-low-protein (HF) and high-protein-low-fiber
(HP) diets on microbial catabolism of tryptophan in the proximal colon (PC) and distal colon …