Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …
[HTML][HTML] Neurodegenerative diseases–is metabolic deficiency the root cause?
VR Muddapu, SAP Dharshini… - Frontiers in …, 2020 - frontiersin.org
Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …
Effect of high‐caloric nutrition on survival in amyotrophic lateral sclerosis
AC Ludolph, J Dorst, J Dreyhaupt… - Annals of …, 2020 - Wiley Online Library
Objective Weight loss has been identified as a negative prognostic factor in amyotrophic
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …
Hypermetabolism in ALS is associated with greater functional decline and shorter survival
Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …
[HTML][HTML] Energy metabolism in ALS: an underappreciated opportunity?
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
[HTML][HTML] Role of brain liver X receptor in Parkinson's disease: hidden treasure and emerging opportunities
Parkinson's disease (PD) is a neurodegenerative disease due to the degeneration of
dopaminergic neurons (DNs) in the substantia nigra (SN). The liver X receptor (LXR) is …
dopaminergic neurons (DNs) in the substantia nigra (SN). The liver X receptor (LXR) is …
[HTML][HTML] Hypothalamic alterations in neurodegenerative diseases and their relation to abnormal energy metabolism
P Vercruysse, D Vieau, D Blum, Å Petersén… - Frontiers in molecular …, 2018 - frontiersin.org
Neurodegenerative diseases (NDDs) are disorders characterized by progressive
deterioration of brain structure and function. Selective neuronal populations are affected …
deterioration of brain structure and function. Selective neuronal populations are affected …
Hypothalamic atrophy is related to body mass index and age at onset in amyotrophic lateral sclerosis
M Gorges, P Vercruysse, HP Müller… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective Our objective was to study the hypothalamic volume in a cohort of patients with
amyotrophic lateral sclerosis (ALS) including symptomatic and presymptomatic ALS …
amyotrophic lateral sclerosis (ALS) including symptomatic and presymptomatic ALS …
[HTML][HTML] Eating behavior in aging and dementia: the need for a comprehensive assessment
S Fostinelli, R De Amicis, A Leone, V Giustizieri… - Frontiers in …, 2020 - frontiersin.org
Eating behavior can change during aging due to physiological, psychological, and social
changes. Modifications can occur at different levels:(1) in food choice,(2) in eating habits …
changes. Modifications can occur at different levels:(1) in food choice,(2) in eating habits …
[HTML][HTML] Transcranial magnetic stimulation for the assessment of neurodegenerative disease
S Vucic, MC Kiernan - Neurotherapeutics, 2017 - Elsevier
Transcranial magnetic stimulation (TMS) is a noninvasive technique that has provided
important information about cortical function across an array of neurodegenerative …
important information about cortical function across an array of neurodegenerative …