Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Recent advances in cancer immunotherapy—ranging from immune-checkpoint blockade
therapy to adoptive cellular therapy and vaccines—have revolutionized cancer treatment …

With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …

Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Entry of antigen-specific T cells into human tumors is critical for immunotherapy, but the
underlying mechanisms are poorly understood. Here, we combined high-dimensional …

Recent advances in neoantigen research have accelerated the development of tumor
immunotherapies, including adoptive cell therapies (ACTs), cancer vaccines and antibody …

With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that
have shown great promise in the immunotherapy of a wide variety of infectious diseases and …

Immune checkpoint inhibitors (ICIs) targeting PD-1 or PD-L1 have emerged as a
revolutionary treatment strategy for human cancer patients. However, as the response rate to …

The hyperproliferative tumor stroma of pancreatic ductal adenocarcinoma (PDAC) severely
limits drug permeation and constructs an immunosuppressive microenvironment, causing …