[HTML][HTML] Research co-design in health: a rapid overview of reviews
Background Billions of dollars are lost annually in health research that fails to create
meaningful benefits for patients. Engaging in research co-design–the meaningful …
meaningful benefits for patients. Engaging in research co-design–the meaningful …
[HTML][HTML] Lost in translation: the valley of death across preclinical and clinical divide–identification of problems and overcoming obstacles
AA Seyhan - Translational Medicine Communications, 2019 - Springer
A rift that has opened up between basic research (bench) and clinical research and patients
(bed) who need their new treatments, diagnostics and prevention, and this rift is widening …
(bed) who need their new treatments, diagnostics and prevention, and this rift is widening …
[HTML][HTML] Control of confounding and reporting of results in causal inference studies. Guidance for authors from editors of respiratory, sleep, and critical care journals
The views and recommendations made in this document do not represent the official
position of any publisher or professional medical society. This document has not been …
position of any publisher or professional medical society. This document has not been …
CARE guidelines for case reports: explanation and elaboration document
Background Well-written and transparent case reports (1) reveal early signals of potential
benefits, harms, and information on the use of resources;(2) provide information for clinical …
benefits, harms, and information on the use of resources;(2) provide information for clinical …
[HTML][HTML] Bayesian alternatives to null hypothesis significance testing in biomedical research: a non-technical introduction to Bayesian inference with JASP
R Kelter - BMC Medical Research Methodology, 2020 - Springer
Background Although null hypothesis significance testing (NHST) is the agreed gold
standard in medical decision making and the most widespread inferential framework used in …
standard in medical decision making and the most widespread inferential framework used in …
[HTML][HTML] No raw data, no science: another possible source of the reproducibility crisis
T Miyakawa - Molecular brain, 2020 - Springer
A reproducibility crisis is a situation where many scientific studies cannot be reproduced.
Inappropriate practices of science, such as HARKing, p-hacking, and selective reporting of …
Inappropriate practices of science, such as HARKing, p-hacking, and selective reporting of …
On doing better science: From thrill of discovery to policy implications
J Antonakis - The Leadership Quarterly, 2017 - Elsevier
In this position paper, I argue that the main purpose of research is to discover and report on
phenomena in a truthful manner. Once uncovered, these phenomena can have important …
phenomena in a truthful manner. Once uncovered, these phenomena can have important …
Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions
E Barry, S Roberts, J Oke, S Vijayaraghavan… - bmj, 2017 - bmj.com
Objectives To assess diagnostic accuracy of screening tests for pre-diabetes and efficacy of
interventions (lifestyle or metformin) in preventing onset of type 2 diabetes in people with pre …
interventions (lifestyle or metformin) in preventing onset of type 2 diabetes in people with pre …
[HTML][HTML] Colloidal capsules: nano-and microcapsules with colloidal particle shells
Utilizing colloidal particles for the assembly of the shell of nano-and microcapsules holds
great promise for the tailor-made design of new functional materials. Increasing research …
great promise for the tailor-made design of new functional materials. Increasing research …
[HTML][HTML] Using clinical natural language processing for health outcomes research: overview and actionable suggestions for future advances
The importance of incorporating Natural Language Processing (NLP) methods in clinical
informatics research has been increasingly recognized over the past years, and has led to …
informatics research has been increasingly recognized over the past years, and has led to …