All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors
(PitNET), are mostly benign, but may present various behaviors: invasive,“aggressive” and …

The classification of neuroendocrine neoplasms (NENs) differs between organ systems and
currently causes considerable confusion. A uniform classification framework for NENs at any …

Prevalence and incidence of prolactinomas are approximately 50 per 100,000 and 3–5 new
cases/100,000/year. The pathophysiological mechanism of hyperprolactinemia-induced …

Hyperprolactinaemia is one of the most common problems in clinical endocrinology. It
relates with various aetiologies (physiological, pharmacological, pathological), the …

Context Silent pituitary adenomas are anterior pituitary tumors with hormone synthesis but
without signs or symptoms of hormone hypersecretion. They have been increasingly …

Purpose Non-functioning pituitary adenomas (NFPAs) are associated with impaired well-
being, increased comorbidities, and reduced long-term survival. Data on optimal …

Recent studies have reported the prevalence of pituitary tumors to be~ 1/1000 population.
Many are prolactin-producing tumors that are managed medically, however, the …

The fourth edition of the World Health Organization classification of endocrine tumors has
been recently published. There are two critical changes to the classification for pituitary …

Background Granular cell tumor (GCT) remains a diagnostic clinicopathologic problem
because the exact frequency of its detailed morphological and clinical characteristics is …