Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies
L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
Elucidating the mechanisms of Temozolomide resistance in gliomas and the strategies to overcome the resistance.
Temozolomide (TMZ) is a first-choice alkylating agent inducted as a gold standard therapy
for glioblastoma multiforme (GBM) and astrocytoma. A majority of patients do not respond to …
for glioblastoma multiforme (GBM) and astrocytoma. A majority of patients do not respond to …
Leveraging a disulfidptosis-based signature to improve the survival and drug sensitivity of bladder cancer patients
H Chen, W Yang, Y Li, L Ma, Z Ji - Frontiers in immunology, 2023 - frontiersin.org
Background Disulfidptosis is a recently discovered form of cell death. However, its biological
mechanisms in bladder cancer (BCa) are yet to be understood. Methods Disulfidptosis …
mechanisms in bladder cancer (BCa) are yet to be understood. Methods Disulfidptosis …
[HTML][HTML] Dysregulated FOXM1 signaling in the regulation of cancer stem cells
Since the introduction of the cancer stem cell (CSC) paradigm, significant advances have
been made in understanding the functional and biological plasticity of these elusive …
been made in understanding the functional and biological plasticity of these elusive …
Malignant ascites in ovarian cancer: cellular, acellular, and biophysical determinants of molecular characteristics and therapy response
Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
[HTML][HTML] Role of OCT4 in cancer stem-like cells and chemotherapy resistance
IS Mohiuddin, SJ Wei, MH Kang - … Acta (BBA)-Molecular Basis of Disease, 2020 - Elsevier
Cancer stem-like cells (CSCs) contribute to the tumorigenicity, progression, and
chemoresistance of cancers. It is not known whether CSCs arise from normal stem cells or if …
chemoresistance of cancers. It is not known whether CSCs arise from normal stem cells or if …
Breast cancer stem cells: Features, key drivers and treatment options
J Dittmer - Seminars in cancer biology, 2018 - Elsevier
The current view is that breast cancer is a stem cell disease characterized by the existence
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …
Curcumin suppresses lung cancer stem cells via inhibiting Wnt/β‐catenin and sonic hedgehog pathways
JY Zhu, X Yang, Y Chen, YE Jiang… - Phytotherapy …, 2017 - Wiley Online Library
Cancer stem cells (CSCs) are highly implicated in the progression of human cancers. Thus,
targeting CSCs may be a promising strategy for cancer therapy. Wnt/β‐catenin and Sonic …
targeting CSCs may be a promising strategy for cancer therapy. Wnt/β‐catenin and Sonic …
Transcriptional factors targeting in cancer stem cells for tumor modulation
Abstract Cancer Stem Cells (CSCs) are now considered the primary" seeds" for the onset,
development, metastasis, and recurrence of tumors. Despite therapeutic breakthroughs …
development, metastasis, and recurrence of tumors. Despite therapeutic breakthroughs …
[HTML][HTML] Regulation of cancer stem cells in triple negative breast cancer
N Fultang, M Chakraborty… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Abstract Triple Negative Breast Cancer (TNBC) is the most lethal subtype of breast cancer.
Despite the successes of emerging targeted therapies, relapse, recurrence, and therapy …
Despite the successes of emerging targeted therapies, relapse, recurrence, and therapy …