Cell death represents a basic biological paradigm that governs outcomes and long-term
sequelae in almost every hepatic disease condition. Acute liver failure is characterized by …

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is a leading
cause of cancer-related death worldwide. It is highly refractory to most systemic therapies …

Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality.
The principal treatment is surgical resection or liver transplantation, depending on whether …

Human cancers, including hepatocellular carcinoma (HCC), are characterized by a high
degree of drug resistance in chemotherapy. However, the underlying molecular mechanism …

Sonodynamic therapy (SDT), as a novel non-invasive strategy for eliminating tumor, has the
advantages of deeper tissue penetration, fewer side effects, and better patient compliance …

Curcumin is a natural polyphenolic compound that has promising therapeutic benefits.
However, curcumin suffers from low aqueous solubility and poor bioavailability following …

HCC (hepatocellular carcinoma) is a major health threat for the Chinese population and has
poor prognosis because of strong resistance to chemotherapy in patients. For instance, a …

Glycyrrhetinic acid (GA), the main hydrolysate of glycyrrhizic acid extracted from the root of
licorice, has been used in hepatocellular carcinoma (HCC) therapy. Particularly, GA as a …

Interactions between cancer cells and cancer-associated fibroblasts (CAFs) within the tumor
microenvironment (TME) play an important role in promoting the profibrotic …

Autophagy is a mechanism by which cellular substances are transported to lysosomes for
degradation, allowing the basic transformation of cellular components, and providing energy …