Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active …
BackgroundPrior trials suggest that intravenous racemic ketamine is a highly effective for
treatment-resistant depression (TRD), but phase 3 trials of racemic ketamine are needed …
treatment-resistant depression (TRD), but phase 3 trials of racemic ketamine are needed …
The molecular pathophysiology of depression and the new therapeutics
H Tian, Z Hu, J Xu, C Wang - MedComm, 2022 - Wiley Online Library
Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …
Effects of different doses of esketamine intervention on postpartum depressive symptoms in cesarean section women: a randomized, double-blind, controlled clinical …
SQ Yang, YY Zhou, ST Yang, XY Mao, L Chen… - Journal of Affective …, 2023 - Elsevier
Background The optimal dosage and method of esketamine for postpartum depressive
symptoms (PDS) are unclear. We conducted a randomized controlled trial (RCT) to …
symptoms (PDS) are unclear. We conducted a randomized controlled trial (RCT) to …
[HTML][HTML] A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment …
The strategy of repeated ketamine in open-label and saline-control studies of treatment-
resistant depression suggested greater antidepressant response beyond a single ketamine …
resistant depression suggested greater antidepressant response beyond a single ketamine …
Psilocybin and MDMA for the treatment of trauma-related psychopathology
CIV Bird, NL Modlin, JJH Rucker - International Review of …, 2021 - Taylor & Francis
This review examines the role of trauma in psychiatric morbidity and analogous
psychoneurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress …
psychoneurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress …
Ketamine for depression
Over the last two decades, the dissociative anaesthetic agent ketamine, an uncompetitive N-
Methyl-D-Aspartate (NMDA) receptor antagonist, has emerged as a novel therapy for …
Methyl-D-Aspartate (NMDA) receptor antagonist, has emerged as a novel therapy for …
RETRACTED ARTICLE: Anatomy of a Woebot®(WB001): agent guided CBT for women with postpartum depression
A Darcy, A Beaudette, E Chiauzzi… - Expert Review of …, 2022 - Taylor & Francis
Statement of Retraction Retraction: Anatomy of a Woebot®(WB001): Agent Guided CBT for
women with postpartum depression We, the Editor and Publisher of Expert Review of …
women with postpartum depression We, the Editor and Publisher of Expert Review of …
Ketamine in neuropsychiatric disorders: an update
The discovery of ketamine as a rapid-acting antidepressant led to a new era in the
development of neuropsychiatric therapeutics, one characterized by an antidepressant …
development of neuropsychiatric therapeutics, one characterized by an antidepressant …
The effects of ketamine on cognition in treatment-resistant depression: a systematic review and priority avenues for future research
H Gill, B Gill, NB Rodrigues, O Lipsitz… - Neuroscience & …, 2021 - Elsevier
Replicated evidence has documented cognitive deficits in populations with treatment-
resistant depression (TRD). Approximately 40% of patients with MDD present with …
resistant depression (TRD). Approximately 40% of patients with MDD present with …
Toll-like receptor signaling in depression
Depression is one of the most prevalent, disabling, and costly mental illnesses currently
affecting over 300 million people worldwide. A subset of depressed patients display …
affecting over 300 million people worldwide. A subset of depressed patients display …